Drug profile

The FDA adverse-event record for Dexamethasone + Neomycin + Polymyxin B

21 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Dexamethasone + Neomycin + Polymyxin B. See the species affected, top reactions, and outcomes below.

21
adverse-event reports
0.0%
death-coded share
Dog
most-reported species
6
Corneal ulcer - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
21
Total Reports
0
Deaths Reported
0.0%
Death Rate

Active Ingredients

DexamethasoneDexamethasone + Neomycin + Polymyxin BNeomycinPolymyxin B

Administration Routes

UnknownIntraocularOphthalmicAuricular (Otic)Topical

Species Affected

Dog 18
Cat 3

Most Affected Breeds

Shih Tzu 3
Bulldog - French 2
Chihuahua 2
Spaniel - King Charles Cavalier 2
Poodle (unspecified) 1
Poodle - Miniature 1
Boxer (German Boxer) 1
Poodle - Toy 1
Spaniel - Cocker American 1
Ragdoll 1

Most Reported Reactions

Corneal ulcer 6
Eye disorder NOS (for Photophobia see neurological) 5
Ocular discharge 5
Squinting 4
Neurogenic keratoconjunctivitis sicca (KCS) 4
Abnormal Schirmer tear test 4
Conjunctivitis 3
Dry eye 3
Behavioural disorder NOS 3
Ear infection NOS 3
Schirmer tear test 3
Swollen eye 3

Outcome Breakdown

Ongoing
9 (42.9%)
Outcome Unknown
7 (33.3%)
Recovered/Normal
4 (19.0%)
Recovered with Sequela
1 (4.8%)

Dexamethasone + Neomycin + Polymyxin B Adverse Event Insights

21 reports name Dexamethasone + Neomycin + Polymyxin B; 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). Active ingredients: Dexamethasone, Dexamethasone + Neomycin + Polymyxin B, Neomycin, Polymyxin B. Administration routes: Unknown, Intraocular, Ophthalmic, Auricular (Otic).

By species: Dog (18 reports), Cat (3 reports). By breed: Shih Tzu (3), Bulldog - French (2), Chihuahua (2).

Leading clinical signs: Corneal ulcer (6), Eye disorder NOS (for Photophobia see neurological) (5), Ocular discharge (5), Squinting (4). Outcome, 21 coded reports: Ongoing leads at 42.9%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.