Desoxycortone Pivalate

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512 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
512
Total Reports
19
Deaths Reported
370.0%
Death Rate

Active Ingredients

Desoxycortone Pivalate

Administration Routes

SubcutaneousUnknownParenteralIntramuscularIntravenousSubconjunctivalOral

Species Affected

Dog 472
Unknown 32
Cat 6
Other 1
Human 1

Most Affected Breeds

Retriever - Labrador 55
Unknown 35
Dog (unknown) 30
Retriever - Golden 29
Chihuahua 25
Shepherd Dog - German 19
Pointing Dog - German Short-haired 17
American Pit Bull Terrier 15
Poodle - Standard 13
Maltese 12

Most Reported Reactions

High sodium-potassium ratio (Na:K ratio) 161
Polyuria 97
Polydipsia 93
Vomiting 72
Weight gain 58
Hypokalaemia 54
Diarrhoea 48
Immediate pain upon injection 46
Weight loss 45
Lethargy (see also Central nervous system depression in Neurological) 44
Underdose 38
Lethargy (see also Central nervous system depression in 'Neurological') 33

Outcome Breakdown

Outcome Unknown
258 (53.8%)
Recovered/Normal
122 (25.4%)
Ongoing
78 (16.3%)
Euthanized
11 (2.3%)
Died
8 (1.7%)
Recovered with Sequela
3 (0.6%)

Data Summary

Metric Value
Total adverse event reports 512
Reports involving death 19
Case-fatality rate (reported events) 370.0%
Distinct species in reports 5
Distinct breeds in reports 20
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Desoxycortone Pivalate Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 512 adverse event reports referencing Desoxycortone Pivalate, including 19 reports in which the animal died — a 370.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Desoxycortone Pivalate. Reported administration routes include Subcutaneous, Unknown, Parenteral, Intramuscular. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Desoxycortone Pivalate reports are Dog (472 reports), Unknown (32 reports), Cat (6 reports), with Dog accounting for the largest share. Within those species, Retriever - Labrador (55), Unknown (35), Dog (unknown) (30) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Desoxycortone Pivalate are High sodium-potassium ratio (Na:K ratio) (161), Polyuria (97), Polydipsia (93), Vomiting (72). Of the 480 reports with a coded outcome, Outcome Unknown is the leading category at 53.8%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Desoxycortone Pivalate.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial