Drug profile

The FDA adverse-event record for Desoxycortone Pivalate

594 FDA reports name Desoxycortone Pivalate, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#268 of 2,679
by report volume (all drugs)
594
adverse-event reports
4.5%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Desoxycortone Pivalate ranks #268 of 2679 by total reports (594) and #810 of 1130 by death-coded share (4.5%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#268
This drug, reports of 2679
#810
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Desoxycortone Pivalate has 594 reports now versus 563 in that prior snapshot: 31 more (5.5%).

Report change
+31
Death-coded reports
+2
Death-coded share
+0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Desoxycortone Pivalate changes

Signature read: 594 reports place Desoxycortone Pivalate in the upper third of FDA AER volume (#268 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
594
Total Reports
27
Deaths Reported
4.5%
Death-coded share of reports

Active Ingredients

Desoxycortone Pivalate

Administration Routes

SubcutaneousUnknownIntramuscularParenteralIntravenousSubconjunctivalOral

Species Affected

Dog 541
Unknown 45
Cat 6
Other 1
Human 1

Most Affected Breeds

Retriever - Labrador 61
Unknown 48
Dog (unknown) 33
Retriever - Golden 32
Chihuahua 31
Shepherd Dog - German 21
Pointing Dog - German Short-haired 20
Poodle - Standard 19
American Pit Bull Terrier 16
Crossbred Canine/dog 14

Most Reported Reactions

High sodium-potassium ratio (Na:K ratio) 197
Polyuria 113
Polydipsia 106
Vomiting 87
Weight gain 71
Hypokalaemia 66
Diarrhoea 61
Weight loss 55
Lethargy (see also Central nervous system depression in Neurological) 54
Immediate pain upon injection 52
Decreased appetite 41
Underdose 38

Outcome Breakdown

Outcome Unknown
302 (55.0%)
Recovered/Normal
140 (25.5%)
Ongoing
77 (14.0%)
Euthanized
17 (3.1%)
Died
10 (1.8%)
Recovered with Sequela
3 (0.5%)

Desoxycortone Pivalate: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Desoxycortone Pivalate, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar death-coded share

Nearest other drugs by death-coded share (4.5% here), distinct from the volume row.

What to do with this drug

  • Compare Desoxycortone Pivalate's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Desoxycortone Pivalate (#268 of 2,679 by report volume); death-coded 4.5%. PlainBreed drug row · report volume stamp 594 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →