Drug profile

The FDA adverse-event record for Desoxycorticosterone Pivalate

1,749 FDA reports name Desoxycorticosterone Pivalate, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#122 of 2,679
by report volume (all drugs)
1,749
adverse-event reports
7.4%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Desoxycorticosterone Pivalate ranks #122 of 2679 by total reports (1,749) and #672 of 1130 by death-coded share (7.4%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#122
This drug, reports of 2679
#672
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Desoxycorticosterone Pivalate has 1,749 reports now versus 1,747 in that prior snapshot: 2 more (0.1%).

Report change
+2
Death-coded reports
+1
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Desoxycorticosterone Pivalate changes

Signature read: 1,749 reports place Desoxycorticosterone Pivalate in the upper third of FDA AER volume (#122 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
1,749
Total Reports
130
Deaths Reported
7.4%
Death-coded share of reports

Active Ingredients

Desoxycorticosterone Pivalate

Administration Routes

SubcutaneousIntramuscularUnknownParenteralIntravenousOralOtherOphthalmicCutaneous

Species Affected

Dog 1,577
Unknown 152
Cat 10
Monkey 7
Human 2
Goat 1

Most Affected Breeds

Retriever - Labrador 204
Unknown 155
Crossbred Canine/dog 107
Dog (unknown) 79
Poodle - Standard 78
Chihuahua 53
Beagle 48
Deutsche Dogge, Great Dane 39
Retriever - Golden 39
Pointing Dog - German Short-haired 39

Most Reported Reactions

Immediate pain upon injection 247
Lethargy (see also Central nervous system depression in 'Neurological') 228
Vomiting 204
Polyuria 197
Polydipsia 193
Other abnormal test result NOS 160
High sodium-potassium ratio (Na:K ratio) 160
Diarrhoea 156
Lack of efficacy - NOS 131
Anorexia 124
Vocalisation 118
Weight gain 84

Outcome Breakdown

Recovered/Normal
584 (42.0%)
Outcome Unknown
450 (32.3%)
Ongoing
220 (15.8%)
Died
68 (4.9%)
Euthanized
62 (4.5%)
Recovered with Sequela
8 (0.6%)

Desoxycorticosterone Pivalate: high report volume in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Desoxycorticosterone Pivalate, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

  • Compare Desoxycorticosterone Pivalate's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Desoxycorticosterone Pivalate (#122 of 2,679 by report volume); death-coded 7.4%. PlainBreed drug row · report volume stamp 1,749 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →