Drug profile

The FDA adverse-event record for Desoxycorticosterone

10 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Desoxycorticosterone. See the species affected, top reactions, and outcomes below.

10
adverse-event reports
10.0%
death-coded share
Dog
most-reported species
2
Lethargy (see also Central nervous system depression in 'Neurological') - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
10
Total Reports
1
Deaths Reported
10.0%
Death Rate

Active Ingredients

Desoxycorticosterone

Administration Routes

UnknownIntramuscularOral

Species Affected

Dog 10

Most Affected Breeds

Spaniel - Springer English 1
Collie - Border 1
Corgi - Welsh Pembroke 1
Maltese 1
Chihuahua 1
Crossbred Canine/dog 1
Retriever - Golden 1
Shepherd Dog - German 1
Hound - Basset 1
Retriever (unspecified) 1

Most Reported Reactions

Lethargy (see also Central nervous system depression in 'Neurological') 2
Fever 2
Vomiting 2
Inappetence 2
Thrombocytopenia 1
Anorexia 1
Emesis (multiple) 1
Gait abnormality 1
Limping 1
Diarrhoea 1
Agitation 1
Scaly condition NOS 1

Outcome Breakdown

Ongoing
4 (40.0%)
Outcome Unknown
3 (30.0%)
Recovered/Normal
2 (20.0%)
Died
1 (10.0%)

Desoxycorticosterone Adverse Event Insights

10 reports name Desoxycorticosterone; 1 recorded a death outcome (10.0% of reported events, not a population-level mortality rate). Active ingredient: Desoxycorticosterone. Administration routes: Unknown, Intramuscular, Oral.

By species: Dog (10 reports). By breed: Spaniel - Springer English (1), Collie - Border (1), Corgi - Welsh Pembroke (1).

Leading clinical signs: Lethargy (see also Central nervous system depression in 'Neurological') (2), Fever (2), Vomiting (2), Inappetence (2). Outcome, 10 coded reports: Ongoing leads at 40.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.