Drug profile

The FDA adverse-event record for Des

13 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Des. See the species affected, top reactions, and outcomes below.

13
adverse-event reports
23.1%
death-coded share
Dog
most-reported species
3
Diarrhoea - top reaction
Verify with FDA CVM →
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
13
Total Reports
3
Deaths Reported
23.1%
Death Rate

Active Ingredients

Des

Administration Routes

OralUnknown

Species Affected

Dog 13

Most Affected Breeds

Crossbred Canine/dog 3
Retriever - Labrador 3
Boxer (German Boxer) 1
Collie - Border 1
Newfoundland 1
Poodle - Miniature 1
Shepherd (unspecified) 1
Doberman Pinscher 1
Pointing Dog - German Short-haired 1

Most Reported Reactions

Diarrhoea 3
Unable to stand 3
Loss of hearing 2
Partial deafness 2
Death 2
Knuckling 2
Limb weakness 2
Faecal incontinence 2
Gait abnormality 2
Footpad disorder NOS 2
Bone and joint disorder NOS 2
Leucocytosis NOS 2

Outcome Breakdown

Outcome Unknown
4 (30.8%)
Ongoing
4 (30.8%)
Died
2 (15.4%)
Recovered/Normal
2 (15.4%)
Euthanized
1 (7.7%)

Des Adverse Event Insights

13 reports name Des; 3 recorded a death outcome (23.1% of reported events, not a population-level mortality rate). Active ingredient: Des. Administration routes: Oral, Unknown.

By species: Dog (13 reports). By breed: Crossbred Canine/dog (3), Retriever - Labrador (3), Boxer (German Boxer) (1).

Leading clinical signs: Diarrhoea (3), Unable to stand (3), Loss of hearing (2), Partial deafness (2). Outcome, 13 coded reports: Outcome Unknown leads at 30.8%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.