Drug profile

The FDA adverse-event record for Dappl

10 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Dappl. See the species affected, top reactions, and outcomes below.

10
adverse-event reports
10.0%
death-coded share
Dog
most-reported species
4
Facial swelling (see also Skin) - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
10
Total Reports
1
Deaths Reported
10.0%
Death Rate

Active Ingredients

Dappl

Administration Routes

UnknownSubcutaneous

Species Affected

Dog 10

Most Affected Breeds

Greyhound 2
Crossbred Canine/dog 2
Terrier - Bull - American Pit 1
Shepherd Dog - Australian 1
Terrier - Bull 1
Spaniel - Boykin 1
Poodle (unspecified) 1
Ridgeback - Rhodesian 1

Most Reported Reactions

Facial swelling (see also Skin) 4
Vomiting 3
Lethargy (see also Central nervous system depression in Neurological) 3
Facial swelling (see also 'Skin') 2
Drooling 1
Lethargy (see also Central nervous system depression in 'Neurological') 1
Allergic reaction 1
Hives (see also 'Skin') 1
Pruritus 1
Pain NOS 1
Respiratory sound 1
Death 1

Outcome Breakdown

Ongoing
5 (50.0%)
Recovered/Normal
4 (40.0%)
Died
1 (10.0%)

Dappl Adverse Event Insights

10 reports name Dappl; 1 recorded a death outcome (10.0% of reported events, not a population-level mortality rate). Active ingredient: Dappl. Administration routes: Unknown, Subcutaneous.

By species: Dog (10 reports). By breed: Greyhound (2), Crossbred Canine/dog (2), Terrier - Bull - American Pit (1).

Leading clinical signs: Facial swelling (see also Skin) (4), Vomiting (3), Lethargy (see also Central nervous system depression in Neurological) (3), Facial swelling (see also 'Skin') (2). Outcome, 10 coded reports: Ongoing leads at 50.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.