Drug profile

The FDA adverse-event record for Dapp Vaccine

191 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Dapp Vaccine. See the species affected, top reactions, and outcomes below.

191
adverse-event reports
15.7%
death-coded share
Dog
most-reported species
52
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
191
Total Reports
30
Deaths Reported
15.7%
Death Rate

Active Ingredients

Dapp Vaccine

Administration Routes

UnknownSubcutaneousOral

Species Affected

Dog 191

Most Affected Breeds

Retriever - Labrador 22
Chihuahua 18
Terrier - Yorkshire 17
Retriever - Golden 13
Terrier - Bull - American Pit 11
Bulldog - French 5
Dachshund (unspecified) 5
Shepherd Dog - Australian 5
Siberian Husky 4
Beagle 4

Most Reported Reactions

Vomiting 52
Facial swelling (see also Skin) 29
Lethargy (see also Central nervous system depression in Neurological) 29
Diarrhoea 27
Anaphylaxis 22
Seizure NOS 22
Hives (see also Skin) 20
Death by euthanasia 15
Lethargy (see also Central nervous system depression in 'Neurological') 14
Death 14
Decreased appetite 13
Fever 13

Outcome Breakdown

Ongoing
92 (48.2%)
Recovered/Normal
58 (30.4%)
Died
15 (7.9%)
Euthanized
15 (7.9%)
Outcome Unknown
11 (5.8%)

Dapp Vaccine Adverse Event Insights

191 reports name Dapp Vaccine; 30 recorded a death outcome (15.7% of reported events, not a population-level mortality rate). Active ingredient: Dapp Vaccine. Administration routes: Unknown, Subcutaneous, Oral.

By species: Dog (191 reports). By breed: Retriever - Labrador (22), Chihuahua (18), Terrier - Yorkshire (17).

Leading clinical signs: Vomiting (52), Facial swelling (see also Skin) (29), Lethargy (see also Central nervous system depression in Neurological) (29), Diarrhoea (27). Outcome, 191 coded reports: Ongoing leads at 48.2%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.