Drug profile

The FDA adverse-event record for Cyclosporine 2% Drops (Ophthalmic)

12 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Cyclosporine 2% Drops (Ophthalmic). See the species affected, top reactions, and outcomes below.

12
adverse-event reports
0.0%
death-coded share
Dog
most-reported species
4
Lethargy (see also Central nervous system depression in 'Neurological') - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
12
Total Reports
0
Deaths Reported
0.0%
Death Rate

Active Ingredients

Cyclosporine 2% Drops (Ophthalmic)

Administration Routes

Ophthalmic

Species Affected

Dog 12

Most Affected Breeds

Pug 12

Most Reported Reactions

Lethargy (see also Central nervous system depression in 'Neurological') 4
Vomiting 3
Haematuria 2
Urinary tract infection 2
Urine leakage 1
Other abnormal test result NOS 1
Ocular discharge 1
Tachypnoea 1
Decreased appetite 1
Conjunctivitis 1
Pyuria 1
Impaired vision 1

Outcome Breakdown

Recovered/Normal
8 (66.7%)
Outcome Unknown
4 (33.3%)

Cyclosporine 2% Drops (Ophthalmic) Adverse Event Insights

12 reports name Cyclosporine 2% Drops (Ophthalmic); 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). Active ingredient: Cyclosporine 2% Drops (Ophthalmic). Administration route: Ophthalmic.

By species: Dog (12 reports). By breed: Pug (12).

Leading clinical signs: Lethargy (see also Central nervous system depression in 'Neurological') (4), Vomiting (3), Haematuria (2), Urinary tract infection (2). Outcome, 12 coded reports: Recovered/Normal leads at 66.7%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.