Drug profile

The FDA adverse-event record for Cortisone Inj

52 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Cortisone Inj. See the species affected, top reactions, and outcomes below.

52
adverse-event reports
5.8%
death-coded share
Dog
most-reported species
13
Emesis - top reaction
Verify with FDA CVM →
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
52
Total Reports
3
Deaths Reported
5.8%
Death Rate

Active Ingredients

Cortisone Inj

Administration Routes

UnknownParenteralSubcutaneousIntramuscular

Species Affected

Dog 37
Cat 15

Most Affected Breeds

Domestic Shorthair 8
Chihuahua 5
Shih Tzu 3
Bichon Frise 3
Dog (other) 2
Terrier - Jack Russell 2
Pit Bull 2
Crossbred Canine/dog 2
Domestic Longhair 2
Retriever - Labrador 2

Most Reported Reactions

Emesis 13
Lack of efficacy (ectoparasite) - flea 12
Lethargy (see also Central nervous system depression in 'Neurological') 11
Vomiting 10
Behavioural disorder NOS 8
Decreased appetite 4
Lack of efficacy - NOS 3
Panting 3
Other abnormal test result NOS 3
UNPALATABLE 3
Hair loss NOS 3
Ataxia 2

Outcome Breakdown

Recovered/Normal
23 (44.2%)
Outcome Unknown
20 (38.5%)
Recovered with Sequela
3 (5.8%)
Ongoing
3 (5.8%)
Euthanized
2 (3.8%)
Died
1 (1.9%)

Cortisone Inj Adverse Event Insights

52 reports name Cortisone Inj; 3 recorded a death outcome (5.8% of reported events, not a population-level mortality rate). Active ingredient: Cortisone Inj. Administration routes: Unknown, Parenteral, Subcutaneous, Intramuscular.

By species: Dog (37 reports), Cat (15 reports). By breed: Domestic Shorthair (8), Chihuahua (5), Shih Tzu (3).

Leading clinical signs: Emesis (13), Lack of efficacy (ectoparasite) - flea (12), Lethargy (see also Central nervous system depression in 'Neurological') (11), Vomiting (10). Outcome, 52 coded reports: Recovered/Normal leads at 44.2%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.