Drug profile

The FDA adverse-event record for Cortisone Inj

52 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Cortisone Inj. Species, reactions, and outcomes follow.

#1090 of 2,679
by report volume (all drugs)
52
adverse-event reports
5.8%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Cortisone Inj ranks #1088 of 2679 by total reports (52) and #747 of 1130 by death-coded share (5.8%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1088
This drug, reports of 2679
#747
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Cortisone Inj has 52 reports now versus 52 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Cortisone Inj changes

Signature read: Cortisone Inj's 5.8% death-coded share is among the lowest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
52
Total Reports
3
Deaths Reported
5.8%
Death-coded share of reports

Active Ingredients

Cortisone Inj

Administration Routes

UnknownParenteralSubcutaneousIntramuscular

Species Affected

Dog 37
Cat 15

Most Affected Breeds

Domestic Shorthair 8
Chihuahua 5
Bichon Frise 3
Shih Tzu 3
Dog (other) 2
Terrier - Jack Russell 2
Pit Bull 2
Crossbred Canine/dog 2
Domestic Longhair 2
Retriever - Labrador 2

Most Reported Reactions

Emesis 13
Lack of efficacy (ectoparasite) - flea 12
Lethargy (see also Central nervous system depression in 'Neurological') 11
Vomiting 10
Behavioural disorder NOS 8
Decreased appetite 4
Lack of efficacy - NOS 3
Panting 3
Other abnormal test result NOS 3
UNPALATABLE 3
Hair loss NOS 3
Ataxia 2

Outcome Breakdown

Recovered/Normal
23 (44.2%)
Outcome Unknown
20 (38.5%)
Recovered with Sequela
3 (5.8%)
Ongoing
3 (5.8%)
Euthanized
2 (3.8%)
Died
1 (1.9%)

Cortisone Inj: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Nationwide drugs with similar profiles

Two openFDA-derived peer sets for Cortisone Inj, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Cortisone Inj (#1090 of 2,679 by report volume); death-coded 5.8%. PlainBreed drug row · death-coded share stamp 5.8% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →