Drug profile

The FDA adverse-event record for Clostridium Chauvoei, Strain F, Lot No. 2-84;Clostridium Novyi, 8296

37 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Clostridium Chauvoei, Strain F, Lot No. 2-84;Clostridium Novyi, 8296. Species, reactions, and outcomes follow.

#1302 of 2,679
by report volume (all drugs)
37
adverse-event reports
89.2%
death-coded share
Cattle
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Clostridium Chauvoei, Strain F, Lot No. 2-84;Clostridium Novyi, 8296 ranks #1300 of 2679 by total reports (37). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1300
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Clostridium Chauvoei, Strain F, Lot No. 2-84;Clostridium Novyi, 8296 has 37 reports now versus 34 in that prior snapshot: 3 more (8.8%).

Report change
+3
Death-coded reports
+3
Death-coded share
+1.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Clostridium Chauvoei, Strain F, Lot No. 2-84;Clostridium Novyi, 8296 changes

Signature read: Clostridium Chauvoei, Strain F, Lot No. 2-84;Clostridium Novyi, 8296's 89.2% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
37
Total Reports
33
Deaths Reported
89.2%
Death-coded share of reports

Active Ingredients

Clostridium Chauvoei, Strain F, Lot No. 2-84;Clostridium Novyi, 8296

Administration Routes

SubcutaneousUnknown

Species Affected

Cattle 37

Most Affected Breeds

Mixed (Cattle) 29
Cattle (other) 3
Limousin 2
Jersey 2
Aberdeen Angus 1

Most Reported Reactions

Death 30
Lack of efficacy - NOS 19
Necropsy performed 16
Injection site swelling 5
Lack of efficacy (bacteria) - Histophilus somni 4
Malaise 3
Decreased appetite 3
Pneumonia 3
Cardiac disorder NOS 3
Lack of efficacy (bacteria) - NOS 3
Anaphylaxis 2
Acute (interstitial) pneumonia/pleuropneumonia 2

Outcome Breakdown

Died
32 (54.2%)
Outcome Unknown
16 (27.1%)
Ongoing
4 (6.8%)
Recovered/Normal
3 (5.1%)
Recovered with Sequela
3 (5.1%)
Euthanized
1 (1.7%)

Clostridium Chauvoei, Strain F, Lot No. 2-84;Clostridium Novyi, 8296: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Clostridium Chauvoei, Strain F, Lot No. 2-84;Clostridium Novyi, 8296 (#1302 of 2,679 by report volume); death-coded 89.2%. PlainBreed drug row · death-coded share stamp 89.2% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →