Drug profile

The FDA adverse-event record for Clostridium Chauvoei, F, Kb; Clostridium Novyi, 8296, Kb; Clostridium Perfringen

36 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Clostridium Chauvoei, F, Kb; Clostridium Novyi, 8296, Kb; Clostridium Perfringen. See the species affected, top reactions, and outcomes below.

36
adverse-event reports
77.8%
death-coded share
Cattle
most-reported species
30
Lack of efficacy (bacteria) - NOS - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
36
Total Reports
28
Deaths Reported
77.8%
Death Rate

Active Ingredients

Clostridium Chauvoei, F, Kb; Clostridium Novyi, 8296, Kb; Clostridium Perfringen

Administration Routes

SubcutaneousUnknownIntramuscular

Species Affected

Cattle 35
Unknown 1

Most Affected Breeds

Cattle (other) 27
Crossbred Bovine/Cattle 5
Aberdeen Angus 1
Cattle (unspecified) 1
Cattle (unknown) 1
Unknown 1

Most Reported Reactions

Lack of efficacy (bacteria) - NOS 30
Death 20
Lack of efficacy - NOS 8
CULTURE/TITER DATA ABNORMAL 7
DEATH-TREATMENT FAILURE 6
PR-LUNG(S), LESION(S) 5
Death by euthanasia 2
Injection site lump 2
Copper deficiency signs 1
Illness NOS 1
Temporary blindness 1
Aggression 1

Outcome Breakdown

Died
28 (43.1%)
Outcome Unknown
22 (33.8%)
Ongoing
7 (10.8%)
Recovered/Normal
5 (7.7%)
Recovered with Sequela
2 (3.1%)
Euthanized
1 (1.5%)

Clostridium Chauvoei, F, Kb; Clostridium Novyi, 8296, Kb; Clostridium Perfringen Adverse Event Insights

36 reports name Clostridium Chauvoei, F, Kb; Clostridium Novyi, 8296, Kb; Clostridium Perfringen; 28 recorded a death outcome (77.8% of reported events, not a population-level mortality rate). Active ingredient: Clostridium Chauvoei, F, Kb; Clostridium Novyi, 8296, Kb; Clostridium Perfringen. Administration routes: Subcutaneous, Unknown, Intramuscular.

By species: Cattle (35 reports), Unknown (1 reports). By breed: Cattle (other) (27), Crossbred Bovine/Cattle (5), Aberdeen Angus (1).

Leading clinical signs: Lack of efficacy (bacteria) - NOS (30), Death (20), Lack of efficacy - NOS (8), CULTURE/TITER DATA ABNORMAL (7). Outcome, 65 coded reports: Died leads at 43.1%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.