Clostr Perf*2/Clos Others*5 Kb

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18 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
18
Total Reports
13
Deaths Reported
7220.0%
Death Rate

Active Ingredients

Clostr Perf*2/Clos Others*5 Kb

Administration Routes

SubcutaneousUnknown

Species Affected

Cattle 18

Most Affected Breeds

Aberdeen Angus 7
Cattle (other) 5
Holstein-Friesian also known as Holstein 1
Hereford cattle 1
Crossbred Bovine/Cattle 1
Cattle (unknown) 1
Cattle (unspecified) 1
Highland 1

Most Reported Reactions

Death 10
Lack of efficacy - NOS 6
Lack of efficacy (bacteria) - NOS 5
Found dead 4
Elevated temperature 2
Death by euthanasia 2
Lameness 2
Bloated 2
Excessive appetite 2
Abnormal stool colouration 2
Anorexia 1
Lethargy (see also Central nervous system depression in 'Neurological') 1

Outcome Breakdown

Died
13 (35.1%)
Ongoing
9 (24.3%)
Recovered/Normal
8 (21.6%)
Outcome Unknown
5 (13.5%)
Euthanized
2 (5.4%)

Data Summary

Metric Value
Total adverse event reports 18
Reports involving death 13
Case-fatality rate (reported events) 7220.0%
Distinct species in reports 1
Distinct breeds in reports 8
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Clostr Perf*2/Clos Others*5 Kb Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 18 adverse event reports referencing Clostr Perf*2/Clos Others*5 Kb, including 13 reports in which the animal died — a 7220.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Clostr Perf*2/Clos Others*5 Kb. Reported administration routes include Subcutaneous, Unknown. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Clostr Perf*2/Clos Others*5 Kb reports are Cattle (18 reports), with Cattle accounting for the largest share. Within those species, Aberdeen Angus (7), Cattle (other) (5), Holstein-Friesian also known as Holstein (1) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Clostr Perf*2/Clos Others*5 Kb are Death (10), Lack of efficacy - NOS (6), Lack of efficacy (bacteria) - NOS (5), Found dead (4). Of the 37 reports with a coded outcome, Died is the leading category at 35.1%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Clostr Perf*2/Clos Others*5 Kb.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial