Drug profile

The FDA adverse-event record for Clostr Perf*2/Clos Others*5 Kb

18 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Clostr Perf*2/Clos Others*5 Kb. See the species affected, top reactions, and outcomes below.

18
adverse-event reports
72.2%
death-coded share
Cattle
most-reported species
10
Death - top reaction
Verify with FDA CVM →
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
18
Total Reports
13
Deaths Reported
72.2%
Death Rate

Active Ingredients

Clostr Perf*2/Clos Others*5 Kb

Administration Routes

SubcutaneousUnknown

Species Affected

Cattle 18

Most Affected Breeds

Aberdeen Angus 7
Cattle (other) 5
Holstein-Friesian also known as Holstein 1
Hereford cattle 1
Crossbred Bovine/Cattle 1
Cattle (unknown) 1
Cattle (unspecified) 1
Highland 1

Most Reported Reactions

Death 10
Lack of efficacy - NOS 6
Lack of efficacy (bacteria) - NOS 5
Found dead 4
Elevated temperature 2
Death by euthanasia 2
Lameness 2
Bloated 2
Excessive appetite 2
Abnormal stool colouration 2
Anorexia 1
Lethargy (see also Central nervous system depression in 'Neurological') 1

Outcome Breakdown

Died
13 (35.1%)
Ongoing
9 (24.3%)
Recovered/Normal
8 (21.6%)
Outcome Unknown
5 (13.5%)
Euthanized
2 (5.4%)

Clostr Perf*2/Clos Others*5 Kb Adverse Event Insights

18 reports name Clostr Perf*2/Clos Others*5 Kb; 13 recorded a death outcome (72.2% of reported events, not a population-level mortality rate). Active ingredient: Clostr Perf*2/Clos Others*5 Kb. Administration routes: Subcutaneous, Unknown.

By species: Cattle (18 reports). By breed: Aberdeen Angus (7), Cattle (other) (5), Holstein-Friesian also known as Holstein (1).

Leading clinical signs: Death (10), Lack of efficacy - NOS (6), Lack of efficacy (bacteria) - NOS (5), Found dead (4). Outcome, 37 coded reports: Died leads at 35.1%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.