Drug profile

The FDA adverse-event record for Clos P*2/Cl Oth*4/Mor Bovis Kb

26 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Clos P*2/Cl Oth*4/Mor Bovis Kb. See the species affected, top reactions, and outcomes below.

26
adverse-event reports
92.3%
death-coded share
Cattle
most-reported species
20
Death - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
26
Total Reports
24
Deaths Reported
92.3%
Death Rate

Active Ingredients

Clos P*2/Cl Oth*4/Mor Bovis Kb

Administration Routes

Subcutaneous

Species Affected

Cattle 26

Most Affected Breeds

Crossbred Bovine/Cattle 9
Cattle (other) 9
Red Angus 6
Cattle (unspecified) 1
Aberdeen Angus 1

Most Reported Reactions

Death 20
Found dead 5
Lack of efficacy - NOS 5
Anaphylaxis 4
Lack of efficacy (bacteria) - NOS 4
NT - Abnormal necropsy finding NOS 3
Breathing difficulty 3
Foam in the nose 3
Foam in the mouth 3
Respiratory distress 3
Anaphylactic-type reaction 3
Lateral recumbency 2

Outcome Breakdown

Died
24 (68.6%)
Ongoing
6 (17.1%)
Recovered/Normal
4 (11.4%)
Outcome Unknown
1 (2.9%)

Clos P*2/Cl Oth*4/Mor Bovis Kb Adverse Event Insights

26 reports name Clos P*2/Cl Oth*4/Mor Bovis Kb; 24 recorded a death outcome (92.3% of reported events, not a population-level mortality rate). Active ingredient: Clos P*2/Cl Oth*4/Mor Bovis Kb. Administration route: Subcutaneous.

By species: Cattle (26 reports). By breed: Crossbred Bovine/Cattle (9), Cattle (other) (9), Red Angus (6).

Leading clinical signs: Death (20), Found dead (5), Lack of efficacy - NOS (5), Anaphylaxis (4). Outcome, 35 coded reports: Died leads at 68.6%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.