Clomipramine
693 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
693
Total Reports
12
Deaths Reported
170.0%
Death Rate
Active Ingredients
Clomipramine
Administration Routes
OralUnknownRespiratory (Inhalation)
Species Affected
Dog 353
Unknown 281
Cat 31
Human 28
Most Affected Breeds
Unknown 310
Crossbred Canine/dog 39
Retriever - Labrador 30
Shih Tzu 15
Domestic Shorthair 13
Shepherd Dog - German 13
Pit Bull 12
Retriever - Golden 12
Terrier - Yorkshire 11
Beagle 11
Most Reported Reactions
Tablets, Abnormal 252
Uncoded sign 209
Lack of efficacy - NOS 81
Vomiting 68
Lethargy (see also Central nervous system depression in 'Neurological') 45
Diarrhoea 40
Behavioural disorder NOS 33
Accidental exposure 32
Elevated alanine aminotransferase (ALT) 30
Elevated serum alkaline phosphatase (SAP) 28
Other abnormal test result NOS 27
Weight loss 26
Outcome Breakdown
Outcome Unknown
126 (38.8%)
Recovered/Normal
93 (28.6%)
Ongoing
88 (27.1%)
Died
8 (2.5%)
Recovered with Sequela
6 (1.8%)
Euthanized
4 (1.2%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.