Drug profile

The FDA adverse-event record for Clindamycin Hydrochloride

297 FDA reports name Clindamycin Hydrochloride, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#425 of 2,679
by report volume (all drugs)
297
adverse-event reports
7.4%
death-coded share
Unknown
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Clindamycin Hydrochloride ranks #424 of 2679 by total reports (297) and #673 of 1130 by death-coded share (7.4%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#424
This drug, reports of 2679
#673
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Clindamycin Hydrochloride has 297 reports now versus 291 in that prior snapshot: 6 more (2.1%).

Report change
+6
Death-coded reports
+0
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Clindamycin Hydrochloride changes

Signature read: 297 reports place Clindamycin Hydrochloride in the upper third of FDA AER volume (#425 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
297
Total Reports
22
Deaths Reported
7.4%
Death-coded share of reports

Active Ingredients

Clindamycin Hydrochloride

Administration Routes

UnknownOralOtherRectal

Species Affected

Unknown 193
Dog 53
Cat 48
Human 2
Horse 1

Most Affected Breeds

Unknown 204
Domestic Shorthair 11
Chihuahua 8
Cat (unknown) 7
Domestic (unspecified) 6
Maine Coon 5
Crossbred Canine/dog 4
Retriever - Labrador 4
Maltese 4
Cat (other) 3

Most Reported Reactions

Seal, Abnormal 88
Contamination, Foreign Object 20
Vomiting 19
Odor, Abnormal 18
Underfilling, Bottles 18
Diarrhoea 17
Bottles, Damaged 15
Anorexia 14
Lethargy (see also Central nervous system depression in 'Neurological') 14
Product Defect, General 12
Containers, Leaking 12
Death 11

Outcome Breakdown

Outcome Unknown
23 (30.3%)
Ongoing
16 (21.1%)
Recovered/Normal
15 (19.7%)
Died
14 (18.4%)
Euthanized
8 (10.5%)

Clindamycin Hydrochloride: high report volume in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Clindamycin Hydrochloride, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar death-coded share

Nearest other drugs by death-coded share (7.4% here), distinct from the volume row.

What to do with this drug

  • Compare Clindamycin Hydrochloride's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Clindamycin Hydrochloride (#425 of 2,679 by report volume); death-coded 7.4%. PlainBreed drug row · report volume stamp 297 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →