Drug profile

The FDA adverse-event record for Clindamycin Hydrochloride

284 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Clindamycin Hydrochloride. See the species affected, top reactions, and outcomes below.

284
adverse-event reports
7.7%
death-coded share
Unknown
most-reported species
80
Seal, Abnormal - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
284
Total Reports
22
Deaths Reported
7.7%
Death Rate

Active Ingredients

Clindamycin Hydrochloride

Administration Routes

UnknownOralOtherRectal

Species Affected

Unknown 182
Dog 53
Cat 46
Human 2
Horse 1

Most Affected Breeds

Unknown 193
Domestic Shorthair 10
Chihuahua 8
Cat (unknown) 7
Domestic (unspecified) 6
Maine Coon 5
Crossbred Canine/dog 4
Retriever - Labrador 4
Maltese 4
Cat (other) 3

Most Reported Reactions

Seal, Abnormal 80
Contamination, Foreign Object 20
Vomiting 19
Odor, Abnormal 17
Underfilling, Bottles 17
Diarrhoea 16
Bottles, Damaged 15
Anorexia 14
Lethargy (see also Central nervous system depression in 'Neurological') 14
Product Defect, General 12
Death 11
Other abnormal test result NOS 11

Outcome Breakdown

Outcome Unknown
22 (29.7%)
Ongoing
16 (21.6%)
Died
14 (18.9%)
Recovered/Normal
14 (18.9%)
Euthanized
8 (10.8%)

Clindamycin Hydrochloride Adverse Event Insights

284 reports name Clindamycin Hydrochloride; 22 recorded a death outcome (7.7% of reported events, not a population-level mortality rate). Active ingredient: Clindamycin Hydrochloride. Administration routes: Unknown, Oral, Other, Rectal.

By species: Unknown (182 reports), Dog (53 reports), Cat (46 reports). By breed: Unknown (193), Domestic Shorthair (10), Chihuahua (8).

Leading clinical signs: Seal, Abnormal (80), Contamination, Foreign Object (20), Vomiting (19), Odor, Abnormal (17). Outcome, 74 coded reports: Outcome Unknown leads at 29.7%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.