Drug profile

The FDA adverse-event record for Civ Bivalent

13 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Civ Bivalent. See the species affected, top reactions, and outcomes below.

13
adverse-event reports
7.7%
death-coded share
Dog
most-reported species
5
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
13
Total Reports
1
Deaths Reported
7.7%
Death Rate

Active Ingredients

Civ Bivalent

Administration Routes

UnknownSubcutaneous

Species Affected

Dog 13

Most Affected Breeds

Retriever - Labrador 4
Terrier - Bull - American Pit 2
Dachshund - Standard Smooth-haired 1
Bulldog 1
Greyhound - Italian 1
Chihuahua 1
Doberman Pinscher 1
Bulldog - French 1
Shepherd Dog - Australian 1

Most Reported Reactions

Vomiting 5
Facial swelling (see also 'Skin') 4
Hives (see also 'Skin') 4
Panting 3
Seizure NOS 3
Lethargy (see also Central nervous system depression in 'Neurological') 2
Vocalisation 2
Anorexia 2
Anaphylaxis 2
Generalised weakness 1
Ataxia 1
Star-gazing 1

Outcome Breakdown

Ongoing
7 (53.8%)
Recovered/Normal
4 (30.8%)
Euthanized
1 (7.7%)
Outcome Unknown
1 (7.7%)

Civ Bivalent Adverse Event Insights

13 reports name Civ Bivalent; 1 recorded a death outcome (7.7% of reported events, not a population-level mortality rate). Active ingredient: Civ Bivalent. Administration routes: Unknown, Subcutaneous.

By species: Dog (13 reports). By breed: Retriever - Labrador (4), Terrier - Bull - American Pit (2), Dachshund - Standard Smooth-haired (1).

Leading clinical signs: Vomiting (5), Facial swelling (see also 'Skin') (4), Hives (see also 'Skin') (4), Panting (3). Outcome, 13 coded reports: Ongoing leads at 53.8%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.