Drug profile

The FDA adverse-event record for Chondroitin Sulfate

27 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Chondroitin Sulfate. See the species affected, top reactions, and outcomes below.

27
adverse-event reports
11.1%
death-coded share
Dog
most-reported species
5
Vomiting - top reaction
Verify with FDA CVM →
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
27
Total Reports
3
Deaths Reported
11.1%
Death Rate

Active Ingredients

Chondroitin Sulfate

Administration Routes

OralUnknown

Species Affected

Dog 26
Cat 1

Most Affected Breeds

Retriever - Labrador 6
Chihuahua 3
Shepherd Dog - German 2
Siberian Husky 2
Pit Bull 2
Mountain Cur 1
Crossbred Canine/dog 1
Shih Tzu 1
Dachshund - Standard Long-haired 1
Kuvasz 1

Most Reported Reactions

Vomiting 5
Emesis 4
Other abnormal test result NOS 3
Vocalisation 3
Not eating 3
Seizure NOS 3
Lack of efficacy - NOS 3
Lethargy (see also Central nervous system depression in 'Neurological') 3
Elevated liver enzymes 2
Anaemia NOS 2
Thyroid gland disorder NOS 2
Renal disorder NOS 2

Outcome Breakdown

Outcome Unknown
8 (29.6%)
Recovered/Normal
7 (25.9%)
Ongoing
7 (25.9%)
Recovered with Sequela
2 (7.4%)
Euthanized
2 (7.4%)
Died
1 (3.7%)

Chondroitin Sulfate Adverse Event Insights

27 reports name Chondroitin Sulfate; 3 recorded a death outcome (11.1% of reported events, not a population-level mortality rate). Active ingredient: Chondroitin Sulfate. Administration routes: Oral, Unknown.

By species: Dog (26 reports), Cat (1 reports). By breed: Retriever - Labrador (6), Chihuahua (3), Shepherd Dog - German (2).

Leading clinical signs: Vomiting (5), Emesis (4), Other abnormal test result NOS (3), Vocalisation (3). Outcome, 27 coded reports: Outcome Unknown leads at 29.6%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.