Drug profile

The FDA adverse-event record for Chemotherapy Drug

52 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Chemotherapy Drug. Species, reactions, and outcomes follow.

#1089 of 2,679
by report volume (all drugs)
52
adverse-event reports
34.6%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Chemotherapy Drug ranks #1088 of 2679 by total reports (52) and #105 of 1130 by death-coded share (34.6%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1088
This drug, reports of 2679
#105
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Chemotherapy Drug has 52 reports now versus 52 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Chemotherapy Drug changes

Signature read: Chemotherapy Drug's 34.6% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
52
Total Reports
18
Deaths Reported
34.6%
Death-coded share of reports

Active Ingredients

Chemotherapy Drug

Administration Routes

UnknownOralIntravenous

Species Affected

Dog 41
Cat 11

Most Affected Breeds

Domestic Shorthair 6
Shih Tzu 3
Dog (unknown) 3
Terrier - Bull - American Pit 3
Pug 2
Collie - Border 2
Crossbred Canine/dog 2
Boxer (German Boxer) 2
Shepherd Dog - Australian 2
Retriever - Golden 2

Most Reported Reactions

Lethargy (see also Central nervous system depression in 'Neurological') 10
Death by euthanasia 9
Vomiting 8
Death 8
Anorexia 7
Lymphoma 6
Diarrhoea 5
Other abnormal test result NOS 5
Hypoalbuminaemia 5
Weakness 4
Lack of efficacy - NOS 4
Anaemia NOS 4

Outcome Breakdown

Ongoing
20 (38.5%)
Euthanized
9 (17.3%)
Outcome Unknown
9 (17.3%)
Died
9 (17.3%)
Recovered/Normal
5 (9.6%)

Chemotherapy Drug: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Nationwide drugs with similar profiles

Two openFDA-derived peer sets for Chemotherapy Drug, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Chemotherapy Drug (#1089 of 2,679 by report volume); death-coded 34.6%. PlainBreed drug row · death-coded share stamp 34.6% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →