Drug profile

The FDA adverse-event record for Cephapirin Sodium

370 FDA reports name Cephapirin Sodium, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#368 of 2,679
by report volume (all drugs)
370
adverse-event reports
1.4%
death-coded share
Cattle
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Cephapirin Sodium ranks #367 of 2679 by total reports (370) and #1043 of 1130 by death-coded share (1.4%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#367
This drug, reports of 2679
#1043
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Cephapirin Sodium has 370 reports now versus 368 in that prior snapshot: 2 more (0.5%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Cephapirin Sodium changes

Signature read: 370 reports place Cephapirin Sodium in the upper third of FDA AER volume (#368 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
370
Total Reports
5
Deaths Reported
1.4%
Death-coded share of reports

Active Ingredients

Cephapirin Sodium

Administration Routes

IntramammaryUnknownOralTopicalIntramuscularIntralesionalOther

Species Affected

Cattle 288
Unknown 74
Goat 3
Horse 2
Human 1
Dog 1
Sheep 1

Most Affected Breeds

Holstein-Friesian also known as Holstein 200
Unknown 78
Cattle (other) 48
Cattle (unknown) 15
Jersey 14
Crossbred Bovine/Cattle 6
Goat (unknown) 2
Tennessee Walking Horse 1
Goat (other) 1
Ayrshire 1

Most Reported Reactions

Residues in milk 180
Drug dose administration interval too long 74
INEFFECTIVE, ANTIBIOTIC 51
Lack of efficacy (bacteria) - NOS 44
Tubes, Damaged 16
Product syringe issue 13
Tubes, Abnormal 12
Containers, Damaged 12
Product Defect, General 11
Product problem 9
Drug administration duration too long 9
Uncoded sign 8

Outcome Breakdown

Recovered/Normal
139 (52.1%)
Outcome Unknown
115 (43.1%)
Ongoing
6 (2.2%)
Died
3 (1.1%)
Recovered with Sequela
2 (0.7%)
Euthanized
2 (0.7%)

Cephapirin Sodium: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Cephapirin Sodium, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Cephapirin Sodium (#368 of 2,679 by report volume); death-coded 1.4%. PlainBreed drug row · report volume stamp 370 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →