Ceftiofur Crystalline Free Acid

2,078 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
2,078
Total Reports
900
Deaths Reported
4330.0%
Death Rate

Active Ingredients

Ceftiofur Crystalline Free Acid

Administration Routes

IntramuscularUnknownSubcutaneousIntravenousOralTopicalOtherParenteralIntra-ArterialIntradermal

Species Affected

Cattle 959
Horse 844
Unknown 115
Human 74
Pig 33
Cat 14
Donkey 12
Dog 8
Goat 6
Other Equids 4

Most Affected Breeds

Cattle (other) 336
Mixed (Cattle) 334
Quarter Horse 276
Unknown 191
Thoroughbred 153
Holstein-Friesian also known as Holstein 139
Horse (unknown) 102
Warmblood (unspecified) 66
Aberdeen Angus 44
Paint 38

Most Reported Reactions

Death 561
Injection site swelling 464
Lack of efficacy (bacteria) - NOS 340
Lack of efficacy - NOS 276
Injection site pain 234
Fever 159
Death by euthanasia 107
CULTURE/TITER DATA ABNORMAL 91
Colic 83
Injection site inflammation 79
INEFFECTIVE, ANTIBIOTIC 79
Residues in meat/offal 75

Outcome Breakdown

Died
779 (31.2%)
Outcome Unknown
750 (30.1%)
Recovered/Normal
410 (16.4%)
Ongoing
364 (14.6%)
Euthanized
136 (5.5%)
Recovered with Sequela
54 (2.2%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.