Drug profile

The FDA adverse-event record for Cefovecin Sodium

2,850 FDA reports name Cefovecin Sodium, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#79 of 2,679
by report volume (all drugs)
2,850
adverse-event reports
19.1%
death-coded share
Cat
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Cefovecin Sodium ranks #79 of 2679 by total reports (2,850) and #257 of 1130 by death-coded share (19.1%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#79
This drug, reports of 2679
#257
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Cefovecin Sodium has 2,850 reports now versus 2,794 in that prior snapshot: 56 more (2.0%).

Report change
+56
Death-coded reports
+6
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Cefovecin Sodium changes

Signature read: death-coded report count at 545 is the most distinctive stamp on Cefovecin Sodium's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
2,850
Total Reports
545
Deaths Reported
19.1%
Death-coded share of reports

Active Ingredients

Cefovecin Sodium

Administration Routes

SubcutaneousUnknownParenteralOtherIntramuscularTopicalOralIntravenousIntraocularRespiratory (Inhalation)

Species Affected

Cat 2,168
Dog 602
Unknown 67
Human 4
Guinea Pig 4
Other 1
Rabbit 1
Mouse 1
Ferret 1
Tiger 1

Most Affected Breeds

Domestic Shorthair 799
Domestic (unspecified) 752
Cat (unknown) 162
Domestic Longhair 113
Unknown 80
Domestic Mediumhair 74
Siamese 61
Crossbred Canine/dog 60
Shih Tzu 46
Chihuahua 46

Most Reported Reactions

Anorexia 425
Vomiting 378
Depression 296
Death 278
Death by euthanasia 249
Behavioural disorder NOS 228
Ataxia 227
Weight loss 220
Anaemia NOS 191
Lack of efficacy (bacteria) - NOS 189
Diarrhoea 184
Not eating 183

Outcome Breakdown

Outcome Unknown
454 (25.3%)
Died
425 (23.7%)
Recovered/Normal
390 (21.7%)
Ongoing
389 (21.6%)
Euthanized
120 (6.7%)
Recovered with Sequela
19 (1.1%)

Cefovecin Sodium: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Cefovecin Sodium, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar report volume

Nearest other drugs by FDA report count (2,850 here).

Similar death-coded share

Nearest other drugs by death-coded share (19.1% here), distinct from the volume row.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Cefovecin Sodium (#79 of 2,679 by report volume); death-coded 19.1%. PlainBreed drug row · death-coded report count stamp 545 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →