Drug profile

The FDA adverse-event record for Carprofen Injectable

25 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Carprofen Injectable. Species, reactions, and outcomes follow.

#1581 of 2,679
by report volume (all drugs)
25
adverse-event reports
24.0%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Carprofen Injectable ranks #1577 of 2679 by total reports (25). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1577
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Carprofen Injectable has 25 reports now versus 22 in that prior snapshot: 3 more (13.6%).

Report change
+3
Death-coded reports
+2
Death-coded share
+5.8 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Carprofen Injectable changes

Signature read: Carprofen Injectable's 24.0% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
25
Total Reports
6
Deaths Reported
24.0%
Death-coded share of reports

Active Ingredients

Carprofen Injectable

Administration Routes

SubcutaneousUnknownParenteral

Species Affected

Dog 25

Most Affected Breeds

Retriever - Labrador 7
Retriever - Golden 3
Crossbred Canine/dog 3
Terrier - Bull - American Pit 2
Pug 1
Terrier - Yorkshire 1
Bulldog 1
Sheepdog - Old English (Bobtail) 1
Bulldog - English 1
Terrier - Bull 1

Most Reported Reactions

Vomiting 6
Not eating 6
Lethargy (see also Central nervous system depression in Neurological) 5
Elevated serum alkaline phosphatase (ALP) 5
Death 4
Loose stool 3
Tarry or black stool (see also haemorrhagic diarrhoea) 3
Fever 3
Leucocytosis NOS 3
Seizure NOS 3
Blood in vomit 2
Diarrhoea 2

Outcome Breakdown

Ongoing
12 (48.0%)
Recovered/Normal
5 (20.0%)
Died
4 (16.0%)
Outcome Unknown
2 (8.0%)
Euthanized
2 (8.0%)

Carprofen Injectable: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Carprofen Injectable (#1581 of 2,679 by report volume); death-coded 24.0%. PlainBreed drug row · death-coded share stamp 24.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →