Caninie Vaccine

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297 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
297
Total Reports
25
Deaths Reported
840.0%
Death Rate

Active Ingredients

Caninie Vaccine

Administration Routes

UnknownNasalOralSubcutaneous

Species Affected

Dog 297

Most Affected Breeds

Terrier - Bull - American Pit 35
Retriever - Labrador 22
Chihuahua 21
Boxer (German Boxer) 15
Terrier - Yorkshire 13
Schnauzer - Miniature 9
Dachshund (unspecified) 8
Terrier (unspecified) 8
Shih Tzu 7
Pug 7

Most Reported Reactions

Vomiting 124
Facial swelling (see also 'Skin') 89
Lethargy (see also Central nervous system depression in 'Neurological') 57
Hives (see also 'Skin') 49
Diarrhoea 42
Anaphylaxis 42
Pale mucous membrane 30
Urticaria 26
Fever 21
Anaphylactoid reaction 18
Seizure NOS 16
Pruritus 16

Outcome Breakdown

Ongoing
136 (45.8%)
Recovered/Normal
123 (41.4%)
Died
15 (5.1%)
Outcome Unknown
13 (4.4%)
Euthanized
10 (3.4%)

Data Summary

Metric Value
Total adverse event reports 297
Reports involving death 25
Case-fatality rate (reported events) 840.0%
Distinct species in reports 1
Distinct breeds in reports 20
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Caninie Vaccine Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 297 adverse event reports referencing Caninie Vaccine, including 25 reports in which the animal died — a 840.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Caninie Vaccine. Reported administration routes include Unknown, Nasal, Oral, Subcutaneous. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Caninie Vaccine reports are Dog (297 reports), with Dog accounting for the largest share. Within those species, Terrier - Bull - American Pit (35), Retriever - Labrador (22), Chihuahua (21) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Caninie Vaccine are Vomiting (124), Facial swelling (see also 'Skin') (89), Lethargy (see also Central nervous system depression in 'Neurological') (57), Hives (see also 'Skin') (49). Of the 297 reports with a coded outcome, Ongoing is the leading category at 45.8%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Caninie Vaccine.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial