Drug profile

The FDA adverse-event record for Canine Parvovirus Strain Nl-35-D, P.35-D, 8-2-80;Canine Parainfluenza Virus, Str

900 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Canine Parvovirus Strain Nl-35-D, P.35-D, 8-2-80;Canine Parainfluenza Virus, Str. See the species affected, top reactions, and outcomes below.

900
adverse-event reports
11.0%
death-coded share
Dog
most-reported species
388
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
900
Total Reports
99
Deaths Reported
11.0%
Death Rate

Active Ingredients

Canine Parvovirus Strain Nl-35-D, P.35-D, 8-2-80;Canine Parainfluenza Virus, Str

Administration Routes

SubcutaneousUnknownOralSubconjunctivalNasal

Species Affected

Dog 900

Most Affected Breeds

Retriever - Labrador 70
Chihuahua 61
Terrier - Yorkshire 51
Terrier - Bull - American Pit 44
Shih Tzu 35
Shepherd Dog - Australian 35
Retriever - Golden 32
Maltese 29
Bulldog - French 28
Boxer (German Boxer) 27

Most Reported Reactions

Vomiting 388
Lethargy (see also Central nervous system depression in 'Neurological') 218
Facial swelling (see also 'Skin') 162
Anaphylaxis 126
Diarrhoea 119
Hives (see also 'Skin') 104
Pale mucous membrane 87
Fever 68
Seizure NOS 67
Not eating 62
Death 49
Anorexia 46

Outcome Breakdown

Ongoing
455 (50.4%)
Recovered/Normal
307 (34.0%)
Died
55 (6.1%)
Euthanized
45 (5.0%)
Outcome Unknown
40 (4.4%)

Canine Parvovirus Strain Nl-35-D, P.35-D, 8-2-80;Canine Parainfluenza Virus, Str Adverse Event Insights

900 reports name Canine Parvovirus Strain Nl-35-D, P.35-D, 8-2-80;Canine Parainfluenza Virus, Str; 99 recorded a death outcome (11.0% of reported events, not a population-level mortality rate). Active ingredient: Canine Parvovirus Strain Nl-35-D, P.35-D, 8-2-80;Canine Parainfluenza Virus, Str. Administration routes: Subcutaneous, Unknown, Oral, Subconjunctival.

By species: Dog (900 reports). By breed: Retriever - Labrador (70), Chihuahua (61), Terrier - Yorkshire (51).

Leading clinical signs: Vomiting (388), Lethargy (see also Central nervous system depression in 'Neurological') (218), Facial swelling (see also 'Skin') (162), Anaphylaxis (126). Outcome, 902 coded reports: Ongoing leads at 50.4%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.