Drug profile

The FDA adverse-event record for Canine Influenza Virus H3N8;Canine Influenza Virus H3N2

398 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Canine Influenza Virus H3N8;Canine Influenza Virus H3N2. See the species affected, top reactions, and outcomes below.

398
adverse-event reports
8.5%
death-coded share
Dog
most-reported species
185
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
398
Total Reports
34
Deaths Reported
8.5%
Death Rate

Active Ingredients

Canine Influenza Virus H3N8;Canine Influenza Virus H3N2

Administration Routes

SubcutaneousUnknownOralNasalOphthalmic

Species Affected

Dog 398

Most Affected Breeds

Retriever - Labrador 43
Terrier - Bull - American Pit 26
Shih Tzu 15
Boxer (German Boxer) 14
Maltese 13
Bulldog - French 13
Terrier (unspecified) 13
Shepherd Dog - German 12
Retriever - Golden 12
Chihuahua 11

Most Reported Reactions

Vomiting 185
Lethargy (see also Central nervous system depression in 'Neurological') 101
Facial swelling (see also 'Skin') 78
Hives (see also 'Skin') 60
Diarrhoea 52
Anaphylaxis 50
Fever 30
Pale mucous membrane 28
Anorexia 25
Allergic reaction 24
Bloody diarrhoea 22
Not eating 20

Outcome Breakdown

Ongoing
206 (51.8%)
Recovered/Normal
140 (35.2%)
Euthanized
18 (4.5%)
Outcome Unknown
18 (4.5%)
Died
16 (4.0%)

Canine Influenza Virus H3N8;Canine Influenza Virus H3N2 Adverse Event Insights

398 reports name Canine Influenza Virus H3N8;Canine Influenza Virus H3N2; 34 recorded a death outcome (8.5% of reported events, not a population-level mortality rate). Active ingredient: Canine Influenza Virus H3N8;Canine Influenza Virus H3N2. Administration routes: Subcutaneous, Unknown, Oral, Nasal.

By species: Dog (398 reports). By breed: Retriever - Labrador (43), Terrier - Bull - American Pit (26), Shih Tzu (15).

Leading clinical signs: Vomiting (185), Lethargy (see also Central nervous system depression in 'Neurological') (101), Facial swelling (see also 'Skin') (78), Hives (see also 'Skin') (60). Outcome, 398 coded reports: Ongoing leads at 51.8%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.