Drug profile

The FDA adverse-event record for Canine Influenza Virus H3N2;Canine Influenza Virus H3N8

400 FDA reports name Canine Influenza Virus H3N2;Canine Influenza Virus H3N8, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#349 of 2,679
by report volume (all drugs)
400
adverse-event reports
9.3%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Canine Influenza Virus H3N2;Canine Influenza Virus H3N8 ranks #349 of 2679 by total reports (400) and #582 of 1130 by death-coded share (9.3%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#349
This drug, reports of 2679
#582
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Canine Influenza Virus H3N2;Canine Influenza Virus H3N8 has 400 reports now versus 372 in that prior snapshot: 28 more (7.5%).

Report change
+28
Death-coded reports
+0
Death-coded share
−0.7 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Canine Influenza Virus H3N2;Canine Influenza Virus H3N8 changes

Signature read: 400 reports place Canine Influenza Virus H3N2;Canine Influenza Virus H3N8 in the upper third of FDA AER volume (#349 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
400
Total Reports
37
Deaths Reported
9.3%
Death-coded share of reports

Active Ingredients

Canine Influenza Virus H3N2;Canine Influenza Virus H3N8

Administration Routes

SubcutaneousUnknownOralNasal

Species Affected

Dog 400

Most Affected Breeds

Retriever - Labrador 36
Chihuahua 23
Retriever - Golden 23
Shepherd Dog - Australian 19
Crossbred Canine/dog 19
Terrier - Bull - American Pit 19
Terrier (unspecified) 18
Terrier - Yorkshire 16
Dachshund (unspecified) 16
Shih Tzu 15

Most Reported Reactions

Vomiting 130
Lethargy (see also Central nervous system depression in Neurological) 92
Facial swelling (see also Skin) 60
Diarrhoea 55
Anaphylaxis 53
Emesis (multiple) 46
Pale mucous membrane 36
Fever 31
Not eating 31
Hives (see also Skin) 29
Anorexia 29
Lack of efficacy - NOS 20

Outcome Breakdown

Ongoing
187 (46.8%)
Recovered/Normal
141 (35.3%)
Outcome Unknown
35 (8.8%)
Euthanized
20 (5.0%)
Died
17 (4.3%)

Canine Influenza Virus H3N2;Canine Influenza Virus H3N8: high report volume in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Canine Influenza Virus H3N2;Canine Influenza Virus H3N8, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

  • Compare Canine Influenza Virus H3N2;Canine Influenza Virus H3N8's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Canine Influenza Virus H3N2;Canine Influenza Virus H3N8 (#349 of 2,679 by report volume); death-coded 9.3%. PlainBreed drug row · report volume stamp 400 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →