Drug profile

The FDA adverse-event record for Canine Influenza Vaccine

323 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Canine Influenza Vaccine. See the species affected, top reactions, and outcomes below.

323
adverse-event reports
8.0%
death-coded share
Dog
most-reported species
125
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
323
Total Reports
26
Deaths Reported
8.0%
Death Rate

Active Ingredients

Canine Influenza Vaccine

Administration Routes

UnknownSubcutaneousParenteralTransdermalTopicalVaginal

Species Affected

Dog 323

Most Affected Breeds

Retriever - Labrador 43
Retriever - Golden 18
Crossbred Canine/dog 16
Shepherd Dog - Australian 14
Shih Tzu 13
Bulldog - French 10
Terrier - Bull - American Pit 9
Pug 8
Boxer (German Boxer) 7
Pit Bull 7

Most Reported Reactions

Vomiting 125
Lethargy (see also Central nervous system depression in 'Neurological') 56
Diarrhoea 36
Facial swelling (see also 'Skin') 30
Other abnormal test result NOS 24
Seizure NOS 24
Hives (see also 'Skin') 21
Anaphylaxis 20
Ataxia 20
Not eating 19
Behavioural disorder NOS 18
Lack of efficacy (endoparasite) - heartworm 18

Outcome Breakdown

Recovered/Normal
129 (39.9%)
Ongoing
100 (31.0%)
Outcome Unknown
65 (20.1%)
Euthanized
15 (4.6%)
Died
11 (3.4%)
Recovered with Sequela
3 (0.9%)

Canine Influenza Vaccine Adverse Event Insights

323 reports name Canine Influenza Vaccine; 26 recorded a death outcome (8.0% of reported events, not a population-level mortality rate). Active ingredient: Canine Influenza Vaccine. Administration routes: Unknown, Subcutaneous, Parenteral, Transdermal.

By species: Dog (323 reports). By breed: Retriever - Labrador (43), Retriever - Golden (18), Crossbred Canine/dog (16).

Leading clinical signs: Vomiting (125), Lethargy (see also Central nervous system depression in 'Neurological') (56), Diarrhoea (36), Facial swelling (see also 'Skin') (30). Outcome, 323 coded reports: Recovered/Normal leads at 39.9%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.