Drug profile

The FDA adverse-event record for Canine Distemper,Parvovirus Vaccine

91 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Canine Distemper,Parvovirus Vaccine. See the species affected, top reactions, and outcomes below.

91
adverse-event reports
16.5%
death-coded share
Dog
most-reported species
34
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
91
Total Reports
15
Deaths Reported
16.5%
Death Rate

Active Ingredients

Canine Distemper,Parvovirus Vaccine

Administration Routes

UnknownParenteralSubcutaneous

Species Affected

Dog 90
Cat 1

Most Affected Breeds

Retriever - Labrador 12
Retriever - Golden 8
Shepherd Dog - Australian 7
Crossbred Canine/dog 7
Chihuahua 6
Pit Bull 4
Dachshund (unspecified) 3
Doberman Pinscher 3
Bulldog - French 3
Boxer (German Boxer) 2

Most Reported Reactions

Vomiting 34
Diarrhoea 17
Death 14
Not eating 12
Other abnormal test result NOS 11
Lack of efficacy (virus) - parvovirus (including feline panleukopenia) 10
Lethargy (see also Central nervous system depression in 'Neurological') 9
Lethargy (see also Central nervous system depression in Neurological) 8
Ataxia 6
Lack of efficacy (endoparasite) - heartworm 6
Fever 5
Seizure NOS 4

Outcome Breakdown

Outcome Unknown
36 (39.6%)
Recovered/Normal
26 (28.6%)
Ongoing
14 (15.4%)
Died
14 (15.4%)
Euthanized
1 (1.1%)

Canine Distemper,Parvovirus Vaccine Adverse Event Insights

91 reports name Canine Distemper,Parvovirus Vaccine; 15 recorded a death outcome (16.5% of reported events, not a population-level mortality rate). Active ingredient: Canine Distemper,Parvovirus Vaccine. Administration routes: Unknown, Parenteral, Subcutaneous.

By species: Dog (90 reports), Cat (1 reports). By breed: Retriever - Labrador (12), Retriever - Golden (8), Shepherd Dog - Australian (7).

Leading clinical signs: Vomiting (34), Diarrhoea (17), Death (14), Not eating (12). Outcome, 91 coded reports: Outcome Unknown leads at 39.6%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.