Drug profile

The FDA adverse-event record for Canine Distemper/Parvo Vaccine

32 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Canine Distemper/Parvo Vaccine. See the species affected, top reactions, and outcomes below.

32
adverse-event reports
25.0%
death-coded share
Dog
most-reported species
13
Vomiting - top reaction
Verify with FDA CVM →
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
32
Total Reports
8
Deaths Reported
25.0%
Death Rate

Active Ingredients

Canine Distemper/Parvo Vaccine

Administration Routes

UnknownSubcutaneous

Species Affected

Dog 32

Most Affected Breeds

Collie - Border 4
Chihuahua 4
Dog (unknown) 2
Terrier - Jack Russell 2
Boxer (German Boxer) 2
Retriever - Golden 2
Retriever - Labrador 2
Terrier - Yorkshire 2
Terrier - Bull - American Pit 2
Terrier (unspecified) 2

Most Reported Reactions

Vomiting 13
Lethargy (see also Central nervous system depression in 'Neurological') 8
Facial swelling (see also 'Skin') 8
Anorexia 5
Fever 5
Neutrophilia 4
Seizure NOS 4
Death 4
Diarrhoea 4
Death by euthanasia 4
Emesis 4
Other abnormal test result NOS 3

Outcome Breakdown

Ongoing
14 (43.8%)
Recovered/Normal
8 (25.0%)
Died
4 (12.5%)
Euthanized
4 (12.5%)
Outcome Unknown
2 (6.3%)

Canine Distemper/Parvo Vaccine Adverse Event Insights

32 reports name Canine Distemper/Parvo Vaccine; 8 recorded a death outcome (25.0% of reported events, not a population-level mortality rate). Active ingredient: Canine Distemper/Parvo Vaccine. Administration routes: Unknown, Subcutaneous.

By species: Dog (32 reports). By breed: Collie - Border (4), Chihuahua (4), Dog (unknown) (2).

Leading clinical signs: Vomiting (13), Lethargy (see also Central nervous system depression in 'Neurological') (8), Facial swelling (see also 'Skin') (8), Anorexia (5). Outcome, 32 coded reports: Ongoing leads at 43.8%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.