Drug profile

The FDA adverse-event record for Canine Distemper Virus + Hepatitis + Parvovirus + Parainfluenza Virus

16 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Canine Distemper Virus + Hepatitis + Parvovirus + Parainfluenza Virus. See the species affected, top reactions, and outcomes below.

16
adverse-event reports
6.3%
death-coded share
Dog
most-reported species
8
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
16
Total Reports
1
Deaths Reported
6.3%
Death Rate

Active Ingredients

Canine Distemper Virus + Hepatitis + Parvovirus + Parainfluenza Virus

Administration Routes

UnknownParenteralSubcutaneous

Species Affected

Dog 16

Most Affected Breeds

Shepherd Dog - German 2
Retriever - Golden 2
Boxer (German Boxer) 2
Retriever - Labrador 2
Terrier - Yorkshire 2
Shih Tzu 2
Poodle - Standard 1
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 1
Poodle - Miniature 1
Bulldog - English 1

Most Reported Reactions

Vomiting 8
Lack of efficacy (virus) - parvovirus (including feline panleukopenia) 4
Lack of efficacy (endoparasite) - heartworm 4
Diarrhoea 4
Lethargy (see also Central nervous system depression in Neurological) 2
Decreased haematocrit 2
Lack of efficacy (bacteria) - Borrelia 2
Dehydration 2
Lack of efficacy (bacteria) - Anaplasma 2
Weight gain 2
Behavioural disorder NOS 1
Malaise 1

Outcome Breakdown

Outcome Unknown
10 (62.5%)
Recovered/Normal
3 (18.8%)
Ongoing
2 (12.5%)
Died
1 (6.3%)

Canine Distemper Virus + Hepatitis + Parvovirus + Parainfluenza Virus Adverse Event Insights

16 reports name Canine Distemper Virus + Hepatitis + Parvovirus + Parainfluenza Virus; 1 recorded a death outcome (6.3% of reported events, not a population-level mortality rate). Active ingredient: Canine Distemper Virus + Hepatitis + Parvovirus + Parainfluenza Virus. Administration routes: Unknown, Parenteral, Subcutaneous.

By species: Dog (16 reports). By breed: Shepherd Dog - German (2), Retriever - Golden (2), Boxer (German Boxer) (2).

Leading clinical signs: Vomiting (8), Lack of efficacy (virus) - parvovirus (including feline panleukopenia) (4), Lack of efficacy (endoparasite) - heartworm (4), Diarrhoea (4). Outcome, 16 coded reports: Outcome Unknown leads at 62.5%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.