Drug profile

The FDA adverse-event record for Canine Distemper Virus + Adenovirus + Parvovirus + Parainfluenza Virus

Name: Canine Distemper Virus + Adenovirus + Parvovirus + Parainfluenza Virus - FDA Animal Adverse Event Reports
Creator: PlainBreed
License: https://creativecommons.org/publicdomain/zero/1.0/

34 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Canine Distemper Virus + Adenovirus + Parvovirus + Parainfluenza Virus. Species, reactions, and outcomes follow.

#1347 of 2,679
by report volume (all drugs): 34
adverse-event reports: 2.9%
death-coded share: Dog
most-reported species

Compiled by PlainBreed

Verify with FDA CVM →

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Canine Distemper Virus + Adenovirus + Parvovirus + Parainfluenza Virus ranks #1344 of 2679 by total reports (34). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1): 97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1): #1344
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Canine Distemper Virus + Adenovirus + Parvovirus + Parainfluenza Virus has 34 reports now versus 33 in that prior snapshot: 1 more (3.0%).

Report change: +1
Death-coded reports: +0
Death-coded share: −0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Canine Distemper Virus + Adenovirus + Parvovirus + Parainfluenza Virus changes

Signature read: Canine Distemper Virus + Adenovirus + Parvovirus + Parainfluenza Virus's 2.9% death-coded share is among the lowest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

Total Reports

Deaths Reported

2.9%

Death-coded share of reports

Active Ingredients

Canine Distemper Virus + Adenovirus + Parvovirus + Parainfluenza Virus

Administration Routes

UnknownSubcutaneousParenteral

Species Affected

Dog 33

Cat 1

Most Affected Breeds

Retriever - Labrador 5

Shih Tzu 2

Pug 2

Shepherd Dog - Australian 2

Bulldog - American 2

Terrier - Jack Russell 2

Retriever - Golden 2

Great Pyrenees 2

Coonhound (unspecified) 2

Shepherd Dog - German 1

Most Reported Reactions

Lack of efficacy (endoparasite) - heartworm 10

Vomiting 7

Other abnormal test result NOS 5

Anxiety 4

Not eating 4

Lethargy (see also Central nervous system depression in Neurological) 4

Lack of efficacy (virus) - parvovirus (including feline panleukopenia) 3

Behavioural disorder NOS 3

Urine abnormalities NOS 3

Monocytosis 3

Diarrhoea 3

Weight gain 3

Outcome Breakdown

Outcome Unknown

19 (55.9%)

Ongoing

9 (26.5%)

Recovered/Normal

5 (14.7%)

Died

1 (2.9%)

Canine Distemper Virus + Adenovirus + Parvovirus + Parainfluenza Virus: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Canine Distemper Virus + Adenovirus + Parvovirus + Parainfluenza Virus (#1347 of 2,679 by report volume); death-coded 2.9%. PlainBreed drug row · death-coded share stamp 2.9% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →