Drug profile

The FDA adverse-event record for Canine Distemper-Adenovirus Type 2-Coronavirus-Parvovirus Vaccine, Modified Live And Killed Virus

Name: Canine Distemper-Adenovirus Type 2-Coronavirus-Parvovirus Vaccine, Modified Live And Killed Virus - FDA Animal Adverse Event Reports
Creator: PlainBreed
License: https://creativecommons.org/publicdomain/zero/1.0/

15 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Canine Distemper-Adenovirus Type 2-Coronavirus-Parvovirus Vaccine, Modified Live And Killed Virus. See the species affected, top reactions, and outcomes below.

15
adverse-event reports: 20.0%
death-coded share: Dog
most-reported species: 7
Vomiting - top reaction

Compiled by PlainBreed Editorial, Pet Health Editorial Team

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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

Total Reports

Deaths Reported

20.0%

Death Rate

Active Ingredients

Canine Distemper-Adenovirus Type 2-Coronavirus-Parvovirus Vaccine, Modified Live And Killed Virus

Administration Routes

SubcutaneousUnknownParenteral

Species Affected

Dog 15

Most Affected Breeds

Mountain Dog - Bernese 2

Shepherd Dog - Australian 2

Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 2

Dachshund (unspecified) 1

Havanese 1

Poodle - Miniature 1

Chihuahua 1

Terrier - Yorkshire 1

Beagle 1

Spitz - German Pomeranian 1

Most Reported Reactions

Vomiting 7

Lethargy (see also Central nervous system depression in 'Neurological') 4

Lack of efficacy (virus) - parvovirus (including feline panleukopenia) 3

Diarrhoea 3

Emesis 2

Facial swelling (see also 'Skin') 2

Not eating 2

Vocalisation 2

Death 2

Allergic pruritus 1

Anaphylactoid reaction 1

Fever 1

Outcome Breakdown

Recovered/Normal

8 (53.3%)

Outcome Unknown

3 (20.0%)

Died

2 (13.3%)

Euthanized

1 (6.7%)

Ongoing

1 (6.7%)

Canine Distemper-Adenovirus Type 2-Coronavirus-Parvovirus Vaccine, Modified Live And Killed Virus Adverse Event Insights

15 reports name Canine Distemper-Adenovirus Type 2-Coronavirus-Parvovirus Vaccine, Modified Live And Killed Virus; 3 recorded a death outcome (20.0% of reported events, not a population-level mortality rate). Active ingredient: Canine Distemper-Adenovirus Type 2-Coronavirus-Parvovirus Vaccine, Modified Live And Killed Virus. Administration routes: Subcutaneous, Unknown, Parenteral.

By species: Dog (15 reports). By breed: Mountain Dog - Bernese (2), Shepherd Dog - Australian (2), Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) (2).

Leading clinical signs: Vomiting (7), Lethargy (see also Central nervous system depression in 'Neurological') (4), Lack of efficacy (virus) - parvovirus (including feline panleukopenia) (3), Diarrhoea (3). Outcome, 15 coded reports: Recovered/Normal leads at 53.3%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.