Drug profile

The FDA adverse-event record for Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Vaccine, Modified Live And Killed Virus

29 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Vaccine, Modified Live And Killed Virus. See the species affected, top reactions, and outcomes below.

29
adverse-event reports
44.8%
death-coded share
Dog
most-reported species
10
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
29
Total Reports
13
Deaths Reported
44.8%
Death Rate

Active Ingredients

Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Vaccine, Modified Live And Killed Virus

Administration Routes

SubcutaneousParenteralUnknown

Species Affected

Dog 29

Most Affected Breeds

Crossbred Canine/dog 4
Retriever - Golden 3
Poodle - Toy 3
Shih Tzu 3
Retriever - Labrador 2
Boxer (German Boxer) 2
Chihuahua 2
Pit Bull 1
Maltese 1
Shepherd Dog - Australian 1

Most Reported Reactions

Vomiting 10
Death 10
Other abnormal test result NOS 6
Lack of efficacy (virus) - parvovirus (including feline panleukopenia) 6
Diarrhoea 4
Seizure NOS 3
Not eating 3
Lethargy (see also Central nervous system depression in 'Neurological') 3
Elevated serum alkaline phosphatase (SAP) 3
Walking difficulty 2
Low platelet count 2
Platelet disorder NOS 2

Outcome Breakdown

Died
11 (37.9%)
Recovered/Normal
10 (34.5%)
Outcome Unknown
4 (13.8%)
Ongoing
2 (6.9%)
Euthanized
2 (6.9%)

Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Vaccine, Modified Live And Killed Virus Adverse Event Insights

29 reports name Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Vaccine, Modified Live And Killed Virus; 13 recorded a death outcome (44.8% of reported events, not a population-level mortality rate). Active ingredient: Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Vaccine, Modified Live And Killed Virus. Administration routes: Subcutaneous, Parenteral, Unknown.

By species: Dog (29 reports). By breed: Crossbred Canine/dog (4), Retriever - Golden (3), Poodle - Toy (3).

Leading clinical signs: Vomiting (10), Death (10), Other abnormal test result NOS (6), Lack of efficacy (virus) - parvovirus (including feline panleukopenia) (6). Outcome, 29 coded reports: Died leads at 37.9%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.