Drug profile

The FDA adverse-event record for Canine Da2Ppvl Lv/Kb

25 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Canine Da2Ppvl Lv/Kb. See the species affected, top reactions, and outcomes below.

25
adverse-event reports
16.0%
death-coded share
Dog
most-reported species
7
Lethargy (see also Central nervous system depression in 'Neurological') - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
25
Total Reports
4
Deaths Reported
16.0%
Death Rate

Active Ingredients

Canine Da2Ppvl Lv/Kb

Administration Routes

SubcutaneousUnknownOral

Species Affected

Dog 25

Most Affected Breeds

Crossbred Canine/dog 5
Retriever - Labrador 5
Pit Bull 2
Rottweiler 1
Chihuahua 1
Terrier - Silky 1
Greyhound 1
Shepherd Dog - Belgian Malinois 1
Terrier - Irish 1
Siberian Husky 1

Most Reported Reactions

Lethargy (see also Central nervous system depression in 'Neurological') 7
Vomiting 6
Other abnormal test result NOS 3
Anorexia 3
Seizure NOS 3
Pacing 3
Shaking 3
Death 3
Leucopenia NOS 2
Abdominal pain 2
Weight loss 2
Elevated alanine aminotransferase (ALT) 2

Outcome Breakdown

Ongoing
9 (36.0%)
Outcome Unknown
8 (32.0%)
Recovered/Normal
4 (16.0%)
Euthanized
2 (8.0%)
Died
2 (8.0%)

Canine Da2Ppvl Lv/Kb Adverse Event Insights

25 reports name Canine Da2Ppvl Lv/Kb; 4 recorded a death outcome (16.0% of reported events, not a population-level mortality rate). Active ingredient: Canine Da2Ppvl Lv/Kb. Administration routes: Subcutaneous, Unknown, Oral.

By species: Dog (25 reports). By breed: Crossbred Canine/dog (5), Retriever - Labrador (5), Pit Bull (2).

Leading clinical signs: Lethargy (see also Central nervous system depression in 'Neurological') (7), Vomiting (6), Other abnormal test result NOS (3), Anorexia (3). Outcome, 25 coded reports: Ongoing leads at 36.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.