Drug profile

The FDA adverse-event record for Canine B Burgdorferi *2 Alu Kb

398 FDA reports name Canine B Burgdorferi *2 Alu Kb, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#351 of 2,679
by report volume (all drugs)
398
adverse-event reports
3.8%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Canine B Burgdorferi *2 Alu Kb ranks #351 of 2679 by total reports (398) and #862 of 1130 by death-coded share (3.8%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#351
This drug, reports of 2679
#862
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Canine B Burgdorferi *2 Alu Kb has 398 reports now versus 382 in that prior snapshot: 16 more (4.2%).

Report change
+16
Death-coded reports
+1
Death-coded share
+0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Canine B Burgdorferi *2 Alu Kb changes

Signature read: 398 reports place Canine B Burgdorferi *2 Alu Kb in the upper third of FDA AER volume (#351 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
398
Total Reports
15
Deaths Reported
3.8%
Death-coded share of reports

Active Ingredients

Canine B Burgdorferi *2 Alu Kb

Administration Routes

SubcutaneousUnknownOral

Species Affected

Dog 398

Most Affected Breeds

Crossbred Canine/dog 93
Retriever - Labrador 57
Retriever - Golden 37
Shepherd Dog - German 16
Shepherd Dog - Australian 13
Beagle 10
Collie - Border 8
Terrier (unspecified) 7
Boxer (German Boxer) 7
Shih Tzu 6

Most Reported Reactions

Lack of efficacy (bacteria) - Borrelia 186
Lack of efficacy (bacteria) - NOS 104
Lack of efficacy (tick) 101
Lack of efficacy (ectoparasite) - tick NOS 99
Lack of efficacy (bacteria) - Anaplasma 36
Vomiting 24
Emesis (multiple) 14
Lethargy (see also Central nervous system depression in Neurological) 13
Lethargy (see also Central nervous system depression in 'Neurological') 12
Seizure NOS 11
Death by euthanasia 11
Drug dose administration interval too long 10

Outcome Breakdown

Ongoing
267 (67.1%)
Recovered/Normal
89 (22.4%)
Outcome Unknown
25 (6.3%)
Euthanized
11 (2.8%)
Died
4 (1.0%)
Recovered with Sequela
2 (0.5%)

Canine B Burgdorferi *2 Alu Kb: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Canine B Burgdorferi *2 Alu Kb, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

  • Compare Canine B Burgdorferi *2 Alu Kb's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Canine B Burgdorferi *2 Alu Kb (#351 of 2,679 by report volume); death-coded 3.8%. PlainBreed drug row · report volume stamp 398 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →