Drug profile

The FDA adverse-event record for Canine Adenovirus Type 2,Toronto A/26/61,Live + Canine Distemper,Vcp258,Vector + Canine Parvovirus,780916,Live

31 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Canine Adenovirus Type 2,Toronto A/26/61,Live + Canine Distemper,Vcp258,Vector + Canine Parvovirus,780916,Live. Species, reactions, and outcomes follow.

#1414 of 2,679
by report volume (all drugs)
31
adverse-event reports
3.2%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Canine Adenovirus Type 2,Toronto A/26/61,Live + Canine Distemper,Vcp258,Vector + Canine Parvovirus,780916,Live ranks #1412 of 2679 by total reports (31). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1412
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Canine Adenovirus Type 2,Toronto A/26/61,Live + Canine Distemper,Vcp258,Vector + Canine Parvovirus,780916,Live has 31 reports now versus 29 in that prior snapshot: 2 more (6.9%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Canine Adenovirus Type 2,Toronto A/26/61,Live + Canine Distemper,Vcp258,Vector + Canine Parvovirus,780916,Live changes

Signature read: Canine Adenovirus Type 2,Toronto A/26/61,Live + Canine Distemper,Vcp258,Vector + Canine Parvovirus,780916,Live's 3.2% death-coded share is among the lowest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
31
Total Reports
1
Deaths Reported
3.2%
Death-coded share of reports

Active Ingredients

Canine Adenovirus Type 2,Toronto A/26/61,LiveCanine Distemper,Vcp258,VectorCanine Parvovirus,780916,Live

Administration Routes

SubcutaneousUnknown

Species Affected

Dog 31

Most Affected Breeds

Chihuahua 5
Retriever - Golden 3
Pit Bull 2
Spitz - German Pomeranian 2
Terrier - Jack Russell 2
Corgi - Welsh Cardigan 1
Boxer (German Boxer) 1
Spitz - American Eskimo Dog 1
Shiba Inu 1
Havanese 1

Most Reported Reactions

Lethargy (see also Central nervous system depression in 'Neurological') 12
Vomiting 9
Injection site pain 6
Behavioural disorder NOS 4
Injection site swelling 4
Vocalisation 4
Lameness 3
Not eating 3
Lack of efficacy (virus) - parvovirus (including feline panleukopenia) 2
Injection site lump 2
Injection site abscess 2
Diarrhoea 2

Outcome Breakdown

Outcome Unknown
16 (51.6%)
Recovered/Normal
14 (45.2%)
Died
1 (3.2%)

Canine Adenovirus Type 2,Toronto A/26/61,Live + Canine Distemper,Vcp258,Vector + Canine Parvovirus,780916,Live: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Canine Adenovirus Type 2,Toronto A/26/61,Live + Canine Distemper,Vcp258,Vector + Canine Parvovirus,780916,Live (#1414 of 2,679 by report volume); death-coded 3.2%. PlainBreed drug row · death-coded share stamp 3.2% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →