Drug profile

The FDA adverse-event record for Canine Adenovirus, Type 2 Virus, V197 Strain,Canine Distemper Virus, Ondesterpoort Strain,Canine Parainfluenza, 91880 Strain,Canine Parvovirus, Fd 2001 Strain

104 FDA reports name Canine Adenovirus, Type 2 Virus, V197 Strain,Canine Distemper Virus, Ondesterpoort Strain,Canine Parainfluenza, 91880 Strain,Canine Parvovirus, Fd 2001 Strain, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#765 of 2,679
by report volume (all drugs)
104
adverse-event reports
10.6%
death-coded share
Dog
most-reported species
Verify with FDA CVM →

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Canine Adenovirus, Type 2 Virus, V197 Strain,Canine Distemper Virus, Ondesterpoort Strain,Canine Parainfluenza, 91880 Strain,Canine Parvovirus, Fd 2001 Strain ranks #765 of 2679 by total reports (104) and #524 of 1130 by death-coded share (10.6%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#765
This drug, reports of 2679
#524
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Canine Adenovirus, Type 2 Virus, V197 Strain,Canine Distemper Virus, Ondesterpoort Strain,Canine Parainfluenza, 91880 Strain,Canine Parvovirus, Fd 2001 Strain has 104 reports now versus 85 in that prior snapshot: 19 more (22.4%).

Report change
+19
Death-coded reports
+3
Death-coded share
+1.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Canine Adenovirus, Type 2 Virus, V197 Strain,Canine Distemper Virus, Ondesterpoort Strain,Canine Parainfluenza, 91880 Strain,Canine Parvovirus, Fd 2001 Strain changes

Signature read: 104 reports place Canine Adenovirus, Type 2 Virus, V197 Strain,Canine Distemper Virus, Ondesterpoort Strain,Canine Parainfluenza, 91880 Strain,Canine Parvovirus, Fd 2001 Strain in the upper third of FDA AER volume (#765 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
104
Total Reports
11
Deaths Reported
10.6%
Death-coded share of reports

Active Ingredients

Canine Adenovirus, Type 2 Virus, V197 Strain,Canine Distemper Virus, Ondesterpoort Strain,Canine Parainfluenza, 91880 Strain,Canine Parvovirus, Fd 2001 Strain

Administration Routes

SubcutaneousUnknownParenteral

Species Affected

Dog 104

Most Affected Breeds

Retriever - Labrador 12
Dachshund (unspecified) 8
Shepherd Dog - German 7
Shepherd Dog - Australian 6
Crossbred Canine/dog 6
Dachshund - Miniature 5
Terrier - Yorkshire 4
Bulldog - French 4
Terrier - Boston 4
Chihuahua 4

Most Reported Reactions

Vomiting 31
Lack of efficacy (virus) - parvovirus (including feline panleukopenia) 19
Lethargy (see also Central nervous system depression in Neurological) 18
Facial swelling (see also Skin) 17
Other abnormal test result NOS 15
Diarrhoea 15
Lack of efficacy (endoparasite) - heartworm 9
Not eating 9
Hives (see also Skin) 7
Cough 7
Panting 6
Hypersensitivity reaction 6

Outcome Breakdown

Outcome Unknown
42 (39.6%)
Recovered/Normal
39 (36.8%)
Ongoing
14 (13.2%)
Died
6 (5.7%)
Euthanized
5 (4.7%)

Canine Adenovirus, Type 2 Virus, V197 Strain,Canine Distemper Virus, Ondesterpoort Strain,Canine Parainfluenza, 91880 Strain,Canine Parvovirus, Fd 2001 Strain: high report volume in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Canine Adenovirus, Type 2 Virus, V197 Strain,Canine Distemper Virus, Ondesterpoort Strain,Canine Parainfluenza, 91880 Strain,Canine Parvovirus, Fd 2001 Strain, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar death-coded share

Nearest other drugs by death-coded share (10.6% here), distinct from the volume row.

Ciprofloxacin 10.6% Sulfadimethoxine 10.6% Fenbendazol Oral Paste 10.6% Medicated Shampoo 10.6%

What to do with this drug

  • Compare Canine Adenovirus, Type 2 Virus, V197 Strain,Canine Distemper Virus, Ondesterpoort Strain,Canine Parainfluenza, 91880 Strain,Canine Parvovirus, Fd 2001 Strain's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Canine Adenovirus, Type 2 Virus, V197 Strain,Canine Distemper Virus, Ondesterpoort Strain,Canine Parainfluenza, 91880 Strain,Canine Parvovirus, Fd 2001 Strain (#765 of 2,679 by report volume); death-coded 10.6%. PlainBreed drug row · report volume stamp 104 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →