Drug profile

The FDA adverse-event record for Bov.Virus*3

19 FDA reports name Bov.Virus*3, a lower-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#1829 of 2,679
by report volume (all drugs)
19
adverse-event reports
84.2%
death-coded share
Cattle
most-reported species
Verify with FDA CVM →

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Bov.Virus*3 ranks #1827 of 2679 by total reports (19). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1827
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Bov.Virus*3 has 19 reports now versus 18 in that prior snapshot: 1 more (5.6%).

Report change
+1
Death-coded reports
+1
Death-coded share
+0.9 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Bov.Virus*3 changes

Signature read: Bov.Virus*3's 84.2% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
19
Total Reports
16
Deaths Reported
84.2%
Death-coded share of reports

Active Ingredients

Bov.Virus*3

Administration Routes

NasalUnknownIntramuscular

Species Affected

Cattle 19

Most Affected Breeds

Cattle (other) 10
Crossbred Bovine/Cattle 7
Cattle (unspecified) 1
Holstein-Friesian also known as Holstein 1

Most Reported Reactions

Death 16
Lack of efficacy - NOS 8
Lack of efficacy (bacteria) - NOS 5
Lack of efficacy (bacteria NOS) 2
Lack of efficacy (virus) - NOS 2
Paralysis NOS 1
Lateral recumbency 1
Neutrophilia 1
NT - acute (interstitial) pneumonia/pleuropneumonia 1
Myositis 1
Selenium toxicity signs 1
Death by euthanasia 1

Outcome Breakdown

Died
16 (36.4%)
Recovered/Normal
12 (27.3%)
Ongoing
10 (22.7%)
Outcome Unknown
5 (11.4%)
Euthanized
1 (2.3%)

Bov.Virus*3: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Bov.Virus*3 (#1829 of 2,679 by report volume); death-coded 84.2%. PlainBreed drug row · death-coded share stamp 84.2% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →