Drug profile

The FDA adverse-event record for Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza3-Respiratory Syncytial Virus Vaccine

32 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza3-Respiratory Syncytial Virus Vaccine. See the species affected, top reactions, and outcomes below.

32
adverse-event reports
71.9%
death-coded share
Cattle
most-reported species
21
Death - top reaction
Verify with FDA CVM →
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
32
Total Reports
23
Deaths Reported
71.9%
Death Rate

Active Ingredients

Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza3-Respiratory Syncytial Virus Vaccine

Administration Routes

UnknownSubcutaneousParenteral

Species Affected

Cattle 32

Most Affected Breeds

Cattle (unknown) 19
Crossbred Bovine/Cattle 8
Aberdeen Angus 2
Cattle (other) 1
Mixed (Cattle) 1
Red Angus 1

Most Reported Reactions

Death 21
Eye disorder NOS (for photophobia see 'neurological') 8
Skin abscess 8
Claw / hoof / nail disorder NOS 8
Lameness 8
Pneumonia 8
Musculoskeletal disorder NOS 6
Laceration 6
Lack of efficacy (bacteria) - NOS 5
Respiratory signs 5
Ocular discharge 5
Respiratory tract disorder NOS 5

Outcome Breakdown

Died
23 (46.9%)
Outcome Unknown
22 (44.9%)
Recovered/Normal
2 (4.1%)
Euthanized
1 (2.0%)
Ongoing
1 (2.0%)

Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza3-Respiratory Syncytial Virus Vaccine Adverse Event Insights

32 reports name Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza3-Respiratory Syncytial Virus Vaccine; 23 recorded a death outcome (71.9% of reported events, not a population-level mortality rate). Active ingredient: Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza3-Respiratory Syncytial Virus Vaccine. Administration routes: Unknown, Subcutaneous, Parenteral.

By species: Cattle (32 reports). By breed: Cattle (unknown) (19), Crossbred Bovine/Cattle (8), Aberdeen Angus (2).

Leading clinical signs: Death (21), Eye disorder NOS (for photophobia see 'neurological') (8), Skin abscess (8), Claw / hoof / nail disorder NOS (8). Outcome, 49 coded reports: Died leads at 46.9%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.