Drug profile

The FDA adverse-event record for Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza3-Respiratory Syncytial Virus; Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid

11 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza3-Respiratory Syncytial Virus; Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid. See the species affected, top reactions, and outcomes below.

11
adverse-event reports
100.0%
death-coded share
Cattle
most-reported species
10
Death - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
11
Total Reports
11
Deaths Reported
100.0%
Death Rate

Active Ingredients

Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza3-Respiratory Syncytial Virus; Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid

Administration Routes

ParenteralUnknown

Species Affected

Cattle 11

Most Affected Breeds

Aberdeen Angus 4
Cattle (unknown) 3
Mixed (Cattle) 2
Crossbred Bovine/Cattle 1
Holstein-Friesian also known as Holstein 1

Most Reported Reactions

Death 10
Pneumonia 3
Lack of efficacy (bacteria) - NOS 3
NT - Abnormal necropsy finding NOS 3
Respiratory tract disorder NOS 3
Nasal discharge 3
Respiratory signs 2
Recumbency 2
Dyspnoea 2
Hypersalivation 2
Pulmonary fibrosis 2
Pododermatitis 1

Outcome Breakdown

Died
10 (55.6%)
Ongoing
3 (16.7%)
Outcome Unknown
2 (11.1%)
Recovered/Normal
2 (11.1%)
Euthanized
1 (5.6%)

Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza3-Respiratory Syncytial Virus; Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid Adverse Event Insights

11 reports name Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza3-Respiratory Syncytial Virus; Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid; 11 recorded a death outcome (100.0% of reported events, not a population-level mortality rate). Active ingredient: Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza3-Respiratory Syncytial Virus; Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid. Administration routes: Parenteral, Unknown.

By species: Cattle (11 reports). By breed: Aberdeen Angus (4), Cattle (unknown) (3), Mixed (Cattle) (2).

Leading clinical signs: Death (10), Pneumonia (3), Lack of efficacy (bacteria) - NOS (3), NT - Abnormal necropsy finding NOS (3). Outcome, 18 coded reports: Died leads at 55.6%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.