Drug profile

The FDA adverse-event record for Bovine Rhinotraceheitis-Virus Diarrhea-Parainfluenza3-Respiratory Syncytial Virus Vaccine, Modified Live Virus

15 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Bovine Rhinotraceheitis-Virus Diarrhea-Parainfluenza3-Respiratory Syncytial Virus Vaccine, Modified Live Virus. See the species affected, top reactions, and outcomes below.

15
adverse-event reports
86.7%
death-coded share
Cattle
most-reported species
12
Death - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
15
Total Reports
13
Deaths Reported
86.7%
Death Rate

Active Ingredients

Bovine Rhinotraceheitis-Virus Diarrhea-Parainfluenza3-Respiratory Syncytial Virus Vaccine, Modified Live Virus

Administration Routes

SubcutaneousUnknown

Species Affected

Cattle 15

Most Affected Breeds

Cattle (other) 9
Aberdeen Angus 2
Holstein-Friesian also known as Holstein 2
Brangus 1
Crossbred Bovine/Cattle 1

Most Reported Reactions

Death 12
Lethargy (see also Central nervous system depression in 'Neurological') 4
Lack of efficacy - NOS 4
Pneumonia 4
NT - Abnormal necropsy finding NOS 3
Fever 3
Lack of efficacy (protozoa) - Coccidia 2
Respiratory signs 2
Abnormal necropsy finding 2
Anorexia 2
CULTURE/TITER DATA ABNORMAL 2
INEFFECTIVE, WORMS NOS 2

Outcome Breakdown

Died
13 (52.0%)
Recovered/Normal
5 (20.0%)
Outcome Unknown
4 (16.0%)
Ongoing
1 (4.0%)
Recovered with Sequela
1 (4.0%)
Euthanized
1 (4.0%)

Bovine Rhinotraceheitis-Virus Diarrhea-Parainfluenza3-Respiratory Syncytial Virus Vaccine, Modified Live Virus Adverse Event Insights

15 reports name Bovine Rhinotraceheitis-Virus Diarrhea-Parainfluenza3-Respiratory Syncytial Virus Vaccine, Modified Live Virus; 13 recorded a death outcome (86.7% of reported events, not a population-level mortality rate). Active ingredient: Bovine Rhinotraceheitis-Virus Diarrhea-Parainfluenza3-Respiratory Syncytial Virus Vaccine, Modified Live Virus. Administration routes: Subcutaneous, Unknown.

By species: Cattle (15 reports). By breed: Cattle (other) (9), Aberdeen Angus (2), Holstein-Friesian also known as Holstein (2).

Leading clinical signs: Death (12), Lethargy (see also Central nervous system depression in 'Neurological') (4), Lack of efficacy - NOS (4), Pneumonia (4). Outcome, 25 coded reports: Died leads at 52.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.