Drug profile

The FDA adverse-event record for Bovine Respiratory Syncytial Virus, Brsv375, Mlv; Bovine Viral Diarrhea Virus, 5

33 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Bovine Respiratory Syncytial Virus, Brsv375, Mlv; Bovine Viral Diarrhea Virus, 5. See the species affected, top reactions, and outcomes below.

33
adverse-event reports
81.8%
death-coded share
Cattle
most-reported species
28
Lack of efficacy (bacteria) - NOS - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
33
Total Reports
27
Deaths Reported
81.8%
Death Rate

Active Ingredients

Bovine Respiratory Syncytial Virus, Brsv375, Mlv; Bovine Viral Diarrhea Virus, 5

Administration Routes

SubcutaneousUnknownIntramuscular

Species Affected

Cattle 29
Unknown 4

Most Affected Breeds

Cattle (other) 21
Unknown 4
Crossbred Bovine/Cattle 4
Cattle (unknown) 2
Aberdeen Angus 2

Most Reported Reactions

Lack of efficacy (bacteria) - NOS 28
Death 20
Lack of efficacy - NOS 4
PR-LUNG(S), LESION(S) 3
CULTURE/TITER DATA ABNORMAL 3
Missing Cap 3
DEATH-TREATMENT FAILURE 2
Underfilling, Container 2
Pneumonia 1
Lack of efficacy (protozoa) - Coccidia 1
Caps, Abnormal 1
Vials, Leaking 1

Outcome Breakdown

Died
27 (45.8%)
Outcome Unknown
14 (23.7%)
Recovered/Normal
10 (16.9%)
Ongoing
7 (11.9%)
Euthanized
1 (1.7%)

Bovine Respiratory Syncytial Virus, Brsv375, Mlv; Bovine Viral Diarrhea Virus, 5 Adverse Event Insights

33 reports name Bovine Respiratory Syncytial Virus, Brsv375, Mlv; Bovine Viral Diarrhea Virus, 5; 27 recorded a death outcome (81.8% of reported events, not a population-level mortality rate). Active ingredient: Bovine Respiratory Syncytial Virus, Brsv375, Mlv; Bovine Viral Diarrhea Virus, 5. Administration routes: Subcutaneous, Unknown, Intramuscular.

By species: Cattle (29 reports), Unknown (4 reports). By breed: Cattle (other) (21), Unknown (4), Crossbred Bovine/Cattle (4).

Leading clinical signs: Lack of efficacy (bacteria) - NOS (28), Death (20), Lack of efficacy - NOS (4), PR-LUNG(S), LESION(S) (3). Outcome, 59 coded reports: Died leads at 45.8%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.