Drug profile

The FDA adverse-event record for Bovine Parainfluenza Virus 3 (Ts), Rlb103 (Nl-Bk-6), Mlv; Bovine Respiratory Syn

448 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Bovine Parainfluenza Virus 3 (Ts), Rlb103 (Nl-Bk-6), Mlv; Bovine Respiratory Syn. See the species affected, top reactions, and outcomes below.

448
adverse-event reports
85.0%
death-coded share
Cattle
most-reported species
267
Lack of efficacy (bacteria) - NOS - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
448
Total Reports
381
Deaths Reported
85.0%
Death Rate

Active Ingredients

Bovine Parainfluenza Virus 3 (Ts), Rlb103 (Nl-Bk-6), Mlv; Bovine Respiratory Syn

Administration Routes

UnknownNasalSubcutaneousIntramuscularOral

Species Affected

Cattle 445
Unknown 3

Most Affected Breeds

Cattle (other) 226
Mixed (Cattle) 115
Holstein-Friesian also known as Holstein 54
Crossbred Bovine/Cattle 17
Aberdeen Angus 16
Cattle (unknown) 6
Unknown 3
Jersey 3
Hereford cattle 2
Brangus 2

Most Reported Reactions

Lack of efficacy (bacteria) - NOS 267
Death 243
Lack of efficacy - NOS 130
Abnormal test result 51
Unrelated death 46
CULTURE/TITER DATA ABNORMAL 40
Abnormal necropsy finding 34
Increased mortality rate 32
Other abnormal test result NOS 28
NT - Abnormal necropsy finding NOS 23
Death by euthanasia 20
PR-LUNG(S), LESION(S) 16

Outcome Breakdown

Died
373 (48.4%)
Outcome Unknown
278 (36.1%)
Recovered/Normal
48 (6.2%)
Ongoing
45 (5.8%)
Euthanized
15 (1.9%)
Recovered with Sequela
11 (1.4%)

Bovine Parainfluenza Virus 3 (Ts), Rlb103 (Nl-Bk-6), Mlv; Bovine Respiratory Syn Adverse Event Insights

448 reports name Bovine Parainfluenza Virus 3 (Ts), Rlb103 (Nl-Bk-6), Mlv; Bovine Respiratory Syn; 381 recorded a death outcome (85.0% of reported events, not a population-level mortality rate). Active ingredient: Bovine Parainfluenza Virus 3 (Ts), Rlb103 (Nl-Bk-6), Mlv; Bovine Respiratory Syn. Administration routes: Unknown, Nasal, Subcutaneous, Intramuscular.

By species: Cattle (445 reports), Unknown (3 reports). By breed: Cattle (other) (226), Mixed (Cattle) (115), Holstein-Friesian also known as Holstein (54).

Leading clinical signs: Lack of efficacy (bacteria) - NOS (267), Death (243), Lack of efficacy - NOS (130), Abnormal test result (51). Outcome, 770 coded reports: Died leads at 48.4%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.