Bovine Parainfluenza 3 Virus, Modified Live Virus + Bovine Respiratory Syncytial Virus, Modified Live Virus + Bovine Rhinotracheitis Virus, Modified Live Virus + Bovine Virus Diarrhea Type 1, Modified Live Virus + Bovine Virus Diarrhea Type 2, Modified Live Virus + Mannheimia Haemolytica Toxoid
202 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
202
Total Reports
169
Deaths Reported
8370.0%
Death Rate
Active Ingredients
Bovine Parainfluenza 3 Virus, Modified Live VirusBovine Respiratory Syncytial Virus, Modified Live VirusBovine Rhinotracheitis Virus, Modified Live VirusBovine Virus Diarrhea Type 1, Modified Live VirusBovine Virus Diarrhea Type 2, Modified Live VirusMannheimia Haemolytica Toxoid
Administration Routes
UnknownSubcutaneousIntramuscularOther
Species Affected
Cattle 201
Human 1
Most Affected Breeds
Cattle (other) 122
Aberdeen Angus 31
Cattle (unknown) 25
Crossbred Bovine/Cattle 12
Charolais 3
Holstein-Friesian also known as Holstein 2
Brangus 2
Unknown 2
Simmental 1
Piedmont 1
Most Reported Reactions
Death 158
Lack of efficacy - NOS 101
Lack of efficacy (bacteria) - NOS 33
Necropsy performed 17
Death by euthanasia 15
Lack of efficacy (virus) - NOS 15
CULTURE/TITER DATA ABNORMAL 8
Respiratory signs 7
Lack of efficacy (bacteria NOS) 7
Depression 6
Anorexia 5
Other abnormal test result NOS 5
Outcome Breakdown
Died
165 (48.5%)
Outcome Unknown
74 (21.8%)
Recovered/Normal
43 (12.6%)
Ongoing
40 (11.8%)
Euthanized
12 (3.5%)
Recovered with Sequela
6 (1.8%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.