Drug profile

The FDA adverse-event record for Borrelia Burgdorferi Bacterin

475 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Borrelia Burgdorferi Bacterin. See the species affected, top reactions, and outcomes below.

475
adverse-event reports
2.7%
death-coded share
Dog
most-reported species
270
Lack of efficacy (bacteria) - Borrelia - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
475
Total Reports
13
Deaths Reported
2.7%
Death Rate

Active Ingredients

Borrelia Burgdorferi Bacterin

Administration Routes

SubcutaneousParenteralUnknownOther

Species Affected

Dog 475

Most Affected Breeds

Retriever - Labrador 76
Retriever - Golden 56
Shepherd Dog - German 33
Crossbred Canine/dog 20
Collie - Border 19
Shepherd Dog - Australian 18
Beagle 15
Mountain Dog - Bernese 12
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 9
Pit Bull 9

Most Reported Reactions

Lack of efficacy (bacteria) - Borrelia 270
Lack of efficacy (ectoparasite) - tick NOS 123
Other abnormal test result NOS 106
Lethargy (see also Central nervous system depression in 'Neurological') 28
Vomiting 25
Limping 24
Diarrhoea 22
Lack of efficacy (tick) 20
Lack of efficacy (bacteria) - NOS 20
Urine abnormalities NOS 16
Proteinuria 16
Lack of efficacy (bacteria) - Anaplasma 16

Outcome Breakdown

Outcome Unknown
357 (75.2%)
Ongoing
61 (12.8%)
Recovered/Normal
44 (9.3%)
Died
7 (1.5%)
Euthanized
6 (1.3%)

Borrelia Burgdorferi Bacterin Adverse Event Insights

475 reports name Borrelia Burgdorferi Bacterin; 13 recorded a death outcome (2.7% of reported events, not a population-level mortality rate). Active ingredient: Borrelia Burgdorferi Bacterin. Administration routes: Subcutaneous, Parenteral, Unknown, Other.

By species: Dog (475 reports). By breed: Retriever - Labrador (76), Retriever - Golden (56), Shepherd Dog - German (33).

Leading clinical signs: Lack of efficacy (bacteria) - Borrelia (270), Lack of efficacy (ectoparasite) - tick NOS (123), Other abnormal test result NOS (106), Lethargy (see also Central nervous system depression in 'Neurological') (28). Outcome, 475 coded reports: Outcome Unknown leads at 75.2%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.