Drug profile

The FDA adverse-event record for Borrelia Burgdorferi, B-31 Strain,Borrelia Burgdorferi, Ips Strain

108 FDA reports name Borrelia Burgdorferi, B-31 Strain,Borrelia Burgdorferi, Ips Strain, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#750 of 2,679
by report volume (all drugs)
108
adverse-event reports
1.9%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Borrelia Burgdorferi, B-31 Strain,Borrelia Burgdorferi, Ips Strain ranks #749 of 2679 by total reports (108) and #1000 of 1130 by death-coded share (1.9%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#749
This drug, reports of 2679
#1000
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Borrelia Burgdorferi, B-31 Strain,Borrelia Burgdorferi, Ips Strain has 108 reports now versus 89 in that prior snapshot: 19 more (21.3%).

Report change
+19
Death-coded reports
+0
Death-coded share
−0.4 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Borrelia Burgdorferi, B-31 Strain,Borrelia Burgdorferi, Ips Strain changes

Signature read: Borrelia Burgdorferi, B-31 Strain,Borrelia Burgdorferi, Ips Strain's 1.9% death-coded share is among the lowest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
108
Total Reports
2
Deaths Reported
1.9%
Death-coded share of reports

Active Ingredients

Borrelia Burgdorferi, B-31 Strain,Borrelia Burgdorferi, Ips Strain

Administration Routes

SubcutaneousUnknownParenteralOther

Species Affected

Dog 107
Unknown 1

Most Affected Breeds

Retriever - Labrador 14
Retriever - Golden 11
Shepherd Dog - Australian 9
Shepherd Dog - German 9
Siberian Husky 5
Great Pyrenees 5
Crossbred Canine/dog 4
Mountain Dog - Bernese 3
Poodle (unspecified) 2
Beagle 2

Most Reported Reactions

Lack of efficacy (bacteria) - Borrelia 76
Other abnormal test result NOS 22
Lack of efficacy (bacteria) - Anaplasma 15
Lethargy (see also Central nervous system depression in Neurological) 14
Vomiting 12
Weight loss 8
Lack of efficacy (ectoparasite) - tick NOS 8
Diarrhoea 7
Proteinuria 7
Low platelet count 5
Neutrophilia 5
Not eating 5

Outcome Breakdown

Outcome Unknown
82 (76.6%)
Ongoing
15 (14.0%)
Recovered/Normal
8 (7.5%)
Euthanized
2 (1.9%)

Borrelia Burgdorferi, B-31 Strain,Borrelia Burgdorferi, Ips Strain: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Borrelia Burgdorferi, B-31 Strain,Borrelia Burgdorferi, Ips Strain, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar report volume

Nearest other drugs by FDA report count (108 here).

What to do with this drug

  • Compare Borrelia Burgdorferi, B-31 Strain,Borrelia Burgdorferi, Ips Strain's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Borrelia Burgdorferi, B-31 Strain,Borrelia Burgdorferi, Ips Strain (#750 of 2,679 by report volume); death-coded 1.9%. PlainBreed drug row · death-coded share stamp 1.9% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →