Drug profile

The FDA adverse-event record for Bordetella Vaccine

2,008 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Bordetella Vaccine. See the species affected, top reactions, and outcomes below.

2,008
adverse-event reports
8.8%
death-coded share
Dog
most-reported species
599
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
2,008
Total Reports
177
Deaths Reported
8.8%
Death Rate

Active Ingredients

Bordetella Vaccine

Administration Routes

UnknownNasalOralParenteralSubcutaneousIntramuscularOtherIntravenousCutaneous

Species Affected

Dog 2,000
Cat 5
Unknown 2
Human 1

Most Affected Breeds

Retriever - Labrador 209
Retriever - Golden 103
Chihuahua 88
Crossbred Canine/dog 87
Shih Tzu 79
Boxer (German Boxer) 74
Shepherd Dog - German 72
Terrier - Yorkshire 68
Shepherd Dog - Australian 58
Pit Bull 56

Most Reported Reactions

Vomiting 599
Lethargy (see also Central nervous system depression in 'Neurological') 325
Emesis 294
Diarrhoea 248
Other abnormal test result NOS 191
Lethargy (see also Central nervous system depression in Neurological) 130
Not eating 121
Seizure NOS 115
Anorexia 111
Behavioural disorder NOS 106
Emesis (multiple) 98
Decreased appetite 91

Outcome Breakdown

Recovered/Normal
862 (43.0%)
Outcome Unknown
481 (24.0%)
Ongoing
405 (20.2%)
Died
103 (5.1%)
Recovered with Sequela
81 (4.0%)
Euthanized
74 (3.7%)

Bordetella Vaccine Adverse Event Insights

2,008 reports name Bordetella Vaccine; 177 recorded a death outcome (8.8% of reported events, not a population-level mortality rate). Active ingredient: Bordetella Vaccine. Administration routes: Unknown, Nasal, Oral, Parenteral.

By species: Dog (2,000 reports), Cat (5 reports), Unknown (2 reports). By breed: Retriever - Labrador (209), Retriever - Golden (103), Chihuahua (88).

Leading clinical signs: Vomiting (599), Lethargy (see also Central nervous system depression in 'Neurological') (325), Emesis (294), Diarrhoea (248). Outcome, 2,006 coded reports: Recovered/Normal leads at 43.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.