Drug profile

The FDA adverse-event record for Bordetella Oral Vaccine

46 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Bordetella Oral Vaccine. Species, reactions, and outcomes follow.

#1170 of 2,679
by report volume (all drugs)
46
adverse-event reports
10.9%
death-coded share
Dog
most-reported species
Verify with FDA CVM →

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Bordetella Oral Vaccine ranks #1169 of 2679 by total reports (46). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1169
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Bordetella Oral Vaccine has 46 reports now versus 42 in that prior snapshot: 4 more (9.5%).

Report change
+4
Death-coded reports
+0
Death-coded share
−1.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Bordetella Oral Vaccine changes

Signature read: report volume at 46 is the most distinctive stamp on Bordetella Oral Vaccine's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
46
Total Reports
5
Deaths Reported
10.9%
Death-coded share of reports

Active Ingredients

Bordetella Oral Vaccine

Administration Routes

OralUnknown

Species Affected

Dog 46

Most Affected Breeds

Chihuahua 5
Shepherd Dog - German 4
Lhasa Apso 3
Terrier - Bull - American Pit 3
Siberian Husky 3
Bichon Frise 2
Retriever - Labrador 2
Pug 2
Bulldog - American 2
Shih Tzu 2

Most Reported Reactions

Vomiting 15
Lethargy (see also Central nervous system depression in Neurological) 11
Elevated alanine aminotransferase (ALT) 7
Behavioural disorder NOS 6
Anaphylaxis 6
Other abnormal test result NOS 5
Vocalisation 5
Loose stool 5
Diarrhoea 5
Neutrophilia 5
Thrombocytopenia 5
Seizure NOS 4

Outcome Breakdown

Ongoing
19 (41.3%)
Recovered/Normal
13 (28.3%)
Outcome Unknown
8 (17.4%)
Died
3 (6.5%)
Euthanized
2 (4.3%)
Recovered with Sequela
1 (2.2%)

Bordetella Oral Vaccine Adverse Event Insights

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Bordetella Oral Vaccine (#1170 of 2,679 by report volume); death-coded 10.9%. PlainBreed drug row · report volume stamp 46 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →