Drug profile

The FDA adverse-event record for Bordetella Bronchiseptica, Boehringer Ingelheim Strain,Canine Adenovirus Type 2 Virus - Norden Strain,Canine Parainfluenza, 91880 Strain

30 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Bordetella Bronchiseptica, Boehringer Ingelheim Strain,Canine Adenovirus Type 2 Virus - Norden Strain,Canine Parainfluenza, 91880 Strain. Species, reactions, and outcomes follow.

#1442 of 2,679
by report volume (all drugs)
30
adverse-event reports
3.3%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Bordetella Bronchiseptica, Boehringer Ingelheim Strain,Canine Adenovirus Type 2 Virus - Norden Strain,Canine Parainfluenza, 91880 Strain ranks #1440 of 2679 by total reports (30). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1440
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Bordetella Bronchiseptica, Boehringer Ingelheim Strain,Canine Adenovirus Type 2 Virus - Norden Strain,Canine Parainfluenza, 91880 Strain has 30 reports now versus 26 in that prior snapshot: 4 more (15.4%).

Report change
+4
Death-coded reports
+1
Death-coded share
+3.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Bordetella Bronchiseptica, Boehringer Ingelheim Strain,Canine Adenovirus Type 2 Virus - Norden Strain,Canine Parainfluenza, 91880 Strain changes

Signature read: Bordetella Bronchiseptica, Boehringer Ingelheim Strain,Canine Adenovirus Type 2 Virus - Norden Strain,Canine Parainfluenza, 91880 Strain's 3.3% death-coded share is among the lowest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
30
Total Reports
1
Deaths Reported
3.3%
Death-coded share of reports

Active Ingredients

Bordetella Bronchiseptica, Boehringer Ingelheim Strain,Canine Adenovirus Type 2 Virus - Norden Strain,Canine Parainfluenza, 91880 Strain

Administration Routes

NasalUnknownSubcutaneous

Species Affected

Dog 29
Unknown 1

Most Affected Breeds

Shepherd Dog - German 5
Retriever - Golden 3
Crossbred Canine/dog 3
Retriever - Labrador 3
Shih Tzu 2
Spaniel - Springer English 2
Spaniel - King Charles Cavalier 1
Corgi - Welsh Pembroke 1
Shepherd Dog - Australian 1
Poodle - Toy 1

Most Reported Reactions

Diarrhoea 7
Lack of efficacy - NOS 6
Lethargy (see also Central nervous system depression in Neurological) 6
Vomiting 5
Leucocytosis NOS 4
Neutrophilia 4
Other abnormal test result NOS 3
Sneezing 3
Neutropenia 3
Decreased appetite 3
Laboured breathing 2
Panting 2

Outcome Breakdown

Outcome Unknown
15 (51.7%)
Recovered/Normal
9 (31.0%)
Ongoing
4 (13.8%)
Euthanized
1 (3.4%)

Bordetella Bronchiseptica, Boehringer Ingelheim Strain,Canine Adenovirus Type 2 Virus - Norden Strain,Canine Parainfluenza, 91880 Strain: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Bordetella Bronchiseptica, Boehringer Ingelheim Strain,Canine Adenovirus Type 2 Virus - Norden Strain,Canine Parainfluenza, 91880 Strain (#1442 of 2,679 by report volume); death-coded 3.3%. PlainBreed drug row · death-coded share stamp 3.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →