Drug profile

The FDA adverse-event record for Bordetella

474 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Bordetella. See the species affected, top reactions, and outcomes below.

474
adverse-event reports
8.2%
death-coded share
Dog
most-reported species
175
Vomiting - top reaction
Verify with FDA CVM →
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
474
Total Reports
39
Deaths Reported
8.2%
Death Rate

Active Ingredients

Bordetella

Administration Routes

UnknownNasalOralSubcutaneousParenteralIntralesional

Species Affected

Dog 470
Cat 3
Goat 1

Most Affected Breeds

Retriever - Labrador 40
Terrier - Bull - American Pit 36
Crossbred Canine/dog 28
Chihuahua 26
Terrier - Yorkshire 22
Retriever - Golden 21
Shepherd Dog - German 18
Boxer (German Boxer) 16
Shih Tzu 15
Terrier (unspecified) 12

Most Reported Reactions

Vomiting 175
Lethargy (see also Central nervous system depression in 'Neurological') 77
Anaphylaxis 73
Facial swelling (see also 'Skin') 57
Hives (see also 'Skin') 56
Diarrhoea 53
Pale mucous membrane 40
Lethargy (see also Central nervous system depression in Neurological) 37
Seizure NOS 29
Emesis (multiple) 27
Not eating 27
Emesis 25

Outcome Breakdown

Ongoing
194 (40.9%)
Recovered/Normal
188 (39.7%)
Outcome Unknown
53 (11.2%)
Died
20 (4.2%)
Euthanized
19 (4.0%)

Bordetella Adverse Event Insights

474 reports name Bordetella; 39 recorded a death outcome (8.2% of reported events, not a population-level mortality rate). Active ingredient: Bordetella. Administration routes: Unknown, Nasal, Oral, Subcutaneous.

By species: Dog (470 reports), Cat (3 reports), Goat (1 reports). By breed: Retriever - Labrador (40), Terrier - Bull - American Pit (36), Crossbred Canine/dog (28).

Leading clinical signs: Vomiting (175), Lethargy (see also Central nervous system depression in 'Neurological') (77), Anaphylaxis (73), Facial swelling (see also 'Skin') (57). Outcome, 474 coded reports: Ongoing leads at 40.9%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.